Detailed information NTG0124441

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: GT95_RS10140
• Genome accession: NZ_CP008813
• Coordinates: 1956983..1957735 (-)
• Length: 250 a.a.
• NCBI ID: WP_001019933.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain C001
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1951983..1962735

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GT95_RS10105 (GT95_09815)	-	1952040..1952531 (-)	492	WP_000632641.1	PTS sugar transporter subunit IIB	-
GT95_RS10110 (GT95_09820)	-	1952549..1952974 (-)	426	WP_000823122.1	PTS mannose transporter subunit IIA	-
GT95_RS10115 (GT95_09825)	-	1953222..1954256 (-)	1035	WP_000369169.1	acyltransferase family protein	-
GT95_RS10120	-	1954308..1954490 (+)	183	WP_001866975.1	hypothetical protein	-
GT95_RS10125 (GT95_09830)	-	1954485..1955639 (-)	1155	WP_000623426.1	ABC transporter permease subunit	-
GT95_RS10130 (GT95_09835)	-	1955645..1956493 (-)	849	WP_000926589.1	ABC transporter ATP-binding protein	-
GT95_RS11365	-	1956616..1956914 (-)	299	Protein_1896	GHKL domain-containing protein	-
GT95_RS10140 (GT95_09845)	comE/blpR	1956983..1957735 (-)	753	WP_001019933.1	LytTR family transcriptional regulator DNA-binding domain-containing protein	Regulator
GT95_RS10145 (GT95_09850)	-	1958012..1958827 (-)	816	WP_001029869.1	endonuclease/exonuclease/phosphatase family protein	-
GT95_RS10150 (GT95_09855)	-	1958881..1961064 (-)	2184	WP_000795065.1	PTS transporter subunit IIBC	-

Sequence

Protein

• Length: 250 a.a.
• Molecular weight: 29688.18 Da
• Isoelectric Point: 6.4980

>NTDB_id=124441 GT95_RS10140 WP_001019933.1 1956983..1957735(-) (comE/blpR) [Streptococcus agalactiae strain C001]
MNIFILEDDFVQQAHLEKIIKEIRVQYNLHFKTVETFAKPVQLLESIYEIGLHNLFFLDIEIKNDEQIGLEVAKQIRQVD
PYAQIVFVTTHSELMPLTFRYQVSALDYIDKGLSQEEFSQRIEEVLLYVDGICNKPLVENSFYFKSRYSQVQLPFNDLLY
IETSSRSHRVVLYTEKDRMEFTATLGDILKQEPRLFQCHRSFLVNPLNIFKVDRIDRLVYFQNGTTCLISRNKVRDIVSI
VDKYQKDRKR

Nucleotide

• Length: 753 bp

>NTDB_id=124441 GT95_RS10140 WP_001019933.1 1956983..1957735(-) (comE/blpR) [Streptococcus agalactiae strain C001]
GTGAATATTTTTATACTTGAGGATGATTTTGTTCAACAAGCCCATTTGGAAAAAATCATTAAAGAGATTAGAGTACAGTA
CAATCTGCATTTCAAAACAGTAGAAACGTTTGCTAAACCAGTTCAATTATTGGAGTCAATTTATGAAATAGGTTTGCATA
ATTTATTTTTCTTAGATATTGAAATAAAAAACGATGAGCAGATAGGCTTAGAGGTCGCAAAACAAATTAGACAAGTTGAT
CCTTATGCTCAGATTGTTTTTGTTACAACTCATTCAGAATTAATGCCTTTAACCTTTCGTTATCAGGTATCAGCTTTAGA
CTATATCGATAAAGGACTTTCACAGGAAGAGTTTAGCCAAAGGATTGAGGAAGTATTGTTGTACGTAGATGGCATTTGCA
ATAAGCCCTTAGTGGAAAATTCATTCTACTTTAAGTCGCGTTACAGCCAGGTACAATTACCTTTTAACGATCTTCTTTAT
ATAGAAACATCCTCAAGATCACATAGAGTTGTCCTTTATACTGAAAAAGATAGAATGGAATTCACAGCCACTTTGGGGGA
TATTTTAAAACAAGAACCTAGGCTCTTTCAATGTCATCGCTCTTTTTTAGTAAATCCCTTAAATATTTTTAAAGTGGATA
GGATAGATAGATTAGTTTACTTCCAAAATGGAACGACTTGTCTGATTTCACGCAATAAAGTGAGAGATATAGTATCTATA
GTGGATAAATATCAAAAGGATAGAAAAAGATGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (151-238)

• Response regulator receiver domain (Response_reg) (3-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	53.306	96.8	0.516
comE/comE1	Streptococcus equinus JB1	41.152	97.2	0.4
comE	Streptococcus infantis strain Atu-4	37.849	100	0.38
comE	Streptococcus mitis NCTC 12261	38	100	0.38
comE	Streptococcus mitis SK321	38	100	0.38
comE	Streptococcus pneumoniae R6	37.5	99.2	0.372
comE	Streptococcus pneumoniae TIGR4	37.5	99.2	0.372
comE	Streptococcus pneumoniae Rx1	37.5	99.2	0.372
comE	Streptococcus pneumoniae D39	37.5	99.2	0.372