Detailed information NTG0122408

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: EQ90_RS14070
• Genome accession: NZ_CP007674
• Coordinates: 2735558..2736445 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain CA15
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2730558..2741445

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQ90_RS16425	-	2730577..2730669 (+)	93	WP_010956583.1	hypothetical protein	-
EQ90_RS14040 (EQ90_13185)	-	2730777..2731274 (-)	498	WP_001065268.1	glutathione peroxidase	-
EQ90_RS16430	-	2731284..2731544 (-)	261	WP_001789910.1	hypothetical protein	-
EQ90_RS16440	-	2731926..2732039 (-)	114	WP_001791776.1	hypothetical protein	-
EQ90_RS14060 (EQ90_13190)	-	2732698..2734698 (-)	2001	WP_000776751.1	ABC transporter permease	-
EQ90_RS14065 (EQ90_13195)	-	2734695..2735450 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
EQ90_RS14070 (EQ90_13200)	braS	2735558..2736445 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
EQ90_RS14075 (EQ90_13205)	braR	2736456..2737121 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
EQ90_RS16445 (EQ90_13210)	-	2737147..2737347 (-)	201	Protein_2672	hypothetical protein	-
EQ90_RS14090 (EQ90_13215)	-	2737545..2738969 (+)	1425	WP_000953744.1	alkaline phosphatase	-
EQ90_RS16935	-	2739029..2739130 (-)	102	WP_000731972.1	SE2200 family small protein	-
EQ90_RS14095 (EQ90_13225)	-	2739252..2739707 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
EQ90_RS14100 (EQ90_13230)	-	2739952..2740713 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=122408 EQ90_RS14070 WP_000143419.1 2735558..2736445(-) (braS) [Staphylococcus aureus strain CA15]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=122408 EQ90_RS14070 WP_000143419.1 2735558..2736445(-) (braS) [Staphylococcus aureus strain CA15]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997