Detailed information    

insolico Bioinformatically predicted

Overview

Name   cqsS   Type   Regulator
Locus tag   EN18_RS15150 Genome accession   NZ_CP007635
Coordinates   156513..158573 (+) Length   686 a.a.
NCBI ID   WP_001882375.1    Uniprot ID   Q9KM66
Organism   Vibrio cholerae strain 2012EL-2176     
Function   autoinducer sensor (predicted from homology)   
Competence regulation

Genomic Context

Location: 151513..163573
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EN18_RS15140 (EN18_01025) - 152234..153373 (+) 1140 WP_000670244.1 exonuclease SbcCD subunit D -
  EN18_RS15145 (EN18_01030) - 153375..156416 (+) 3042 WP_001247622.1 AAA family ATPase -
  EN18_RS15150 (EN18_01035) cqsS 156513..158573 (+) 2061 WP_001882375.1 quorum-sensing CAI-1 autoinducer sensor kinase/phosphatase CqsS Regulator
  EN18_RS15155 (EN18_01040) cqsA 158802..159971 (-) 1170 WP_001039912.1 alpha-hydroxyketone-type quorum-sensing autoinducer synthase Regulator
  EN18_RS15160 (EN18_01045) - 160168..161130 (-) 963 WP_001104009.1 TDT family transporter -
  EN18_RS15165 (EN18_01050) clcA 161277..162683 (-) 1407 WP_000107451.1 H(+)/Cl(-) exchange transporter ClcA -

Sequence

Protein


Download         Length: 686 a.a.        Molecular weight: 78382.17 Da        Isoelectric Point: 5.3891

>NTDB_id=121974 EN18_RS15150 WP_001882375.1 156513..158573(+) (cqsS) [Vibrio cholerae strain 2012EL-2176]
MIVSMDVIKRVYQYAEPNLSLVGWMGMLGFPAYYFIWEYWFPQSYENLGLRCAAAVLFGGLVFRDSMPKKWQRYMPGYFL
FTIGFCLPFFFAFMMLMNDWSTIWAMSFMASIFLHILLVHDTRVMALQALFSVLVAYLAVYGLTDFHPTTLIEWQYIPIF
LFTYVFGNLCFFRNQISHETKVSIAKTFGAGIAHEMRNPLSALKTSIDVVRTMIPKPQTAAHTDYSLDAQELDLLHQILN
EADDVIYSGNNAIDLLLTSIDENRVSPASFKKHSVVDVIEKAVKTFPYKNAADQHSVELEVHQPFDFFGSDTLLTYALFN
LLKNAFYYQKEHFSVCISIEQTSEHNLIRVRDNGVGIAPEMLEDIFRDFYTFGKNGSYGLGLPFCRKVMSAFGGTIRCAS
QQGQWTEFVLSFPRYDSDTVNEIKTELLKTKSLIYIGSNQAIVRELNQLAVEDEFGFTAISAQQAVRRQDYEFEFDLILL
DLDDATAQGELLPKLEGTLSFAEGCIGYVYDPGKTYAVNINRYLRIQPISIHSILRKPRKIIERLLFEQESLSMNRNVIP
LQKSRHERRILVVDDNQSIRTFTAILLEQQGYEVVQANDGSEVLKHMESQNIDLVLMDIEMPNVGGLEATRLIRNSEHEY
KNIPIIGYTGDNSPKTLALVQTSGMNDFIVKPADRDVLLNKVAAWV

Nucleotide


Download         Length: 2061 bp        

>NTDB_id=121974 EN18_RS15150 WP_001882375.1 156513..158573(+) (cqsS) [Vibrio cholerae strain 2012EL-2176]
GTGATAGTGAGCATGGATGTAATAAAGAGAGTGTATCAATACGCAGAACCTAATCTGTCCTTAGTCGGATGGATGGGCAT
GCTTGGCTTTCCTGCCTACTACTTCATCTGGGAATATTGGTTTCCGCAATCTTACGAAAATTTAGGGCTGCGTTGTGCGG
CAGCGGTGCTGTTCGGTGGGCTGGTGTTTCGTGATTCGATGCCTAAGAAATGGCAGCGGTATATGCCGGGCTATTTTTTA
TTCACCATAGGTTTCTGCTTACCCTTTTTCTTCGCTTTTATGATGTTAATGAATGACTGGTCGACAATTTGGGCCATGTC
GTTTATGGCGTCCATTTTTCTGCATATTCTCTTAGTACACGATACGAGAGTGATGGCGTTACAAGCACTTTTCTCTGTGT
TGGTGGCCTATCTTGCGGTATATGGTTTGACGGATTTTCACCCGACGACTTTGATTGAATGGCAATACATACCGATCTTT
TTGTTTACTTATGTATTTGGGAATTTATGTTTTTTCCGTAACCAAATCTCTCATGAGACCAAAGTGTCGATTGCCAAAAC
GTTCGGAGCGGGGATTGCCCATGAAATGCGTAATCCACTCAGCGCTTTGAAAACGTCGATTGATGTTGTGCGAACCATGA
TCCCTAAACCGCAAACTGCAGCTCATACGGATTATTCCTTGGATGCGCAAGAGCTGGATCTGCTGCATCAAATTTTGAAT
GAAGCTGATGATGTCATCTACTCTGGCAATAACGCGATTGATTTGCTGCTCACCTCGATTGATGAAAACCGTGTCTCTCC
GGCGAGTTTTAAAAAACACTCAGTGGTAGATGTGATTGAAAAAGCAGTGAAAACTTTTCCGTATAAAAATGCAGCGGACC
AGCACTCGGTAGAGCTTGAAGTGCATCAGCCGTTTGACTTTTTTGGCAGTGATACTCTACTGACTTATGCGCTATTTAAC
CTGTTGAAAAATGCCTTCTATTACCAAAAAGAGCATTTCTCGGTTTGTATTTCCATTGAACAAACCAGTGAGCATAACCT
TATTCGAGTCCGTGATAACGGTGTGGGGATTGCGCCAGAGATGTTGGAAGACATTTTCCGTGATTTCTATACCTTCGGTA
AAAATGGTAGCTATGGGCTAGGATTGCCATTTTGCCGCAAAGTGATGTCCGCATTTGGGGGGACGATTCGCTGTGCGTCT
CAACAAGGTCAATGGACAGAATTCGTATTGAGCTTTCCTCGTTACGATTCCGATACGGTTAACGAGATAAAAACAGAACT
GCTGAAAACCAAATCGCTCATTTATATCGGCTCAAATCAAGCTATCGTTCGAGAGTTAAATCAGCTCGCAGTAGAAGATG
AGTTTGGTTTTACCGCTATTTCTGCGCAGCAAGCAGTAAGACGCCAAGATTATGAGTTTGAGTTCGACCTTATTTTGCTC
GACCTTGATGACGCTACGGCGCAGGGAGAACTACTGCCGAAACTTGAAGGGACATTGAGTTTTGCAGAAGGCTGTATCGG
CTATGTGTATGATCCGGGCAAAACGTATGCAGTAAACATTAACCGTTATCTGCGTATCCAACCGATCAGTATTCACTCTA
TTCTCAGAAAGCCGCGGAAAATCATCGAACGCTTGTTGTTTGAGCAAGAATCCTTATCGATGAATCGTAACGTGATCCCC
TTGCAAAAGAGTCGGCATGAACGACGTATTTTGGTGGTTGACGATAATCAATCGATCCGAACTTTTACGGCTATTTTGCT
TGAGCAACAAGGTTATGAAGTGGTGCAAGCCAACGATGGTAGTGAAGTGCTCAAGCATATGGAGAGTCAAAACATCGATT
TAGTATTGATGGACATTGAAATGCCGAATGTCGGGGGATTAGAAGCGACGCGTTTAATTCGTAACTCTGAGCATGAGTAC
AAAAATATTCCGATCATTGGTTACACCGGTGATAACAGCCCCAAAACCTTGGCTCTGGTACAAACCTCTGGCATGAATGA
TTTCATTGTGAAGCCTGCTGACCGTGATGTATTGCTAAATAAAGTGGCAGCTTGGGTGTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(570-682)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(312-413)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9KM66

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cqsS Vibrio cholerae strain A1552

100

100

1

Multiple sequence alignment