Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   SH08_RS21045 Genome accession   NZ_CP010440
Coordinates   4221579..4222211 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli K-12 strain K-12 MG1655     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4216579..4227211
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SH08_RS21015 (SH08_21030) yheS 4216748..4218661 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  SH08_RS21020 (SH08_21035) yheT 4218661..4219683 (+) 1023 WP_000057356.1 hydrolase -
  SH08_RS21025 (SH08_21040) yheU 4219677..4219895 (+) 219 WP_000907085.1 YheU family protein -
  SH08_RS21030 (SH08_21045) prkB 4219949..4220818 (+) 870 WP_001274680.1 phosphoribulokinase -
  SH08_RS21035 (SH08_21050) yhfA 4220873..4221277 (-) 405 WP_001148908.1 OsmC family protein -
  SH08_RS21045 (SH08_21060) crp 4221579..4222211 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  SH08_RS21050 (SH08_21065) yhfK 4222262..4224352 (+) 2091 WP_021553919.1 YccS/YhfK family putative transporter -
  SH08_RS21055 (SH08_21070) argD 4224419..4225639 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  SH08_RS21060 (SH08_21075) pabA 4225725..4226288 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  SH08_RS21065 (SH08_21080) fic 4226320..4226922 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  SH08_RS21070 (SH08_21085) yhfG 4226912..4227079 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=120839 SH08_RS21045 WP_000242755.1 4221579..4222211(+) (crp) [Escherichia coli K-12 strain K-12 MG1655]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=120839 SH08_RS21045 WP_000242755.1 4221579..4222211(+) (crp) [Escherichia coli K-12 strain K-12 MG1655]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467