Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   RG47_RS04105 Genome accession   NZ_CP010169
Coordinates   765441..766073 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain H5     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 760441..771073
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RG47_RS04075 (RG47_03895) yheS 760610..762523 (+) 1914 WP_000634789.1 ABC transporter ATP-binding protein -
  RG47_RS04080 (RG47_03900) yheT 762523..763545 (+) 1023 WP_000057379.1 hydrolase -
  RG47_RS04085 (RG47_03905) yheU 763539..763757 (+) 219 WP_000907085.1 YheU family protein -
  RG47_RS04090 (RG47_03910) prkB 763811..764680 (+) 870 WP_001274680.1 phosphoribulokinase -
  RG47_RS04095 (RG47_03915) yhfA 764735..765139 (-) 405 WP_001148910.1 OsmC family protein -
  RG47_RS04105 (RG47_03925) crp 765441..766073 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  RG47_RS04110 (RG47_03930) yhfK 766124..768214 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  RG47_RS04115 (RG47_03935) argD 768281..769501 (-) 1221 WP_000963787.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  RG47_RS04120 (RG47_03940) pabA 769587..770150 (-) 564 WP_000601856.1 aminodeoxychorismate synthase component 2 -
  RG47_RS04125 (RG47_03945) fic 770182..770784 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  RG47_RS04130 (RG47_03950) yhfG 770774..770941 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=116808 RG47_RS04105 WP_000242755.1 765441..766073(+) (crp) [Escherichia coli strain H5]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=116808 RG47_RS04105 WP_000242755.1 765441..766073(+) (crp) [Escherichia coli strain H5]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment