Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   RG27_RS03560 Genome accession   NZ_CP010121
Coordinates   728188..728820 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain C4     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 723188..733820
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RG27_RS03535 (RG27_03375) yhfG 723322..723489 (+) 168 WP_000736860.1 YhfG family protein -
  RG27_RS03540 (RG27_03380) fic 723479..724081 (+) 603 WP_001280645.1 putative adenosine monophosphate-protein transferase Fic -
  RG27_RS03545 (RG27_03385) pabA 724113..724676 (+) 564 WP_000601857.1 aminodeoxychorismate synthase component 2 -
  RG27_RS03550 (RG27_03390) argD 724762..725982 (+) 1221 WP_000963773.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  RG27_RS03555 (RG27_03395) yhfK 726047..728137 (-) 2091 WP_001306309.1 YccS/YhfK family putative transporter -
  RG27_RS03560 (RG27_03400) crp 728188..728820 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  RG27_RS03570 (RG27_03410) yhfA 729122..729526 (+) 405 WP_001148908.1 OsmC family protein -
  RG27_RS03575 (RG27_03415) prkB 729581..730450 (-) 870 WP_001274675.1 phosphoribulokinase -
  RG27_RS03580 (RG27_03420) yheU 730504..730722 (-) 219 WP_000907085.1 YheU family protein -
  RG27_RS03585 (RG27_03425) yheT 730716..731738 (-) 1023 WP_000057419.1 hydrolase -
  RG27_RS03590 (RG27_03430) yheS 731738..733651 (-) 1914 WP_000634839.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=115336 RG27_RS03560 WP_000242755.1 728188..728820(-) (crp) [Escherichia coli strain C4]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=115336 RG27_RS03560 WP_000242755.1 728188..728820(-) (crp) [Escherichia coli strain C4]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGATGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment