Detailed information NTG1142843

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DQL26_RS06045
• Genome accession: NZ_LS483521
• Coordinates: 1203700..1204737 (-)
• Length: 345 a.a.
• NCBI ID: WP_111693301.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC8316
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1198700..1209737

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL26_RS06020 (NCTC8316_01207)	-	1198704..1199231 (-)	528	WP_014635585.1	Dps family protein	-
DQL26_RS06025 (NCTC8316_01208)	-	1199459..1200085 (+)	627	WP_002989076.1	prepilin peptidase	-
DQL26_RS06030 (NCTC8316_01209)	rlmN	1200167..1201246 (-)	1080	WP_002992788.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
DQL26_RS06035 (NCTC8316_01210)	-	1201250..1201870 (-)	621	WP_002992791.1	YutD family protein	-
DQL26_RS06040 (NCTC8316_01212)	-	1202318..1203295 (-)	978	WP_109991723.1	LacI family DNA-binding transcriptional regulator	-
DQL26_RS06045 (NCTC8316_01213)	sepM	1203700..1204737 (-)	1038	WP_111693301.1	SepM family pheromone-processing serine protease	Regulator
DQL26_RS06050 (NCTC8316_01214)	coaD	1204724..1205215 (-)	492	WP_002983821.1	pantetheine-phosphate adenylyltransferase	-
DQL26_RS06055 (NCTC8316_01215)	rsmD	1205205..1205744 (-)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DQL26_RS06060 (NCTC8316_01216)	asnA	1205867..1206859 (-)	993	WP_023611792.1	aspartate--ammonia ligase	-
DQL26_RS06065 (NCTC8316_01217)	arcC	1207173..1208123 (-)	951	WP_009880962.1	carbamate kinase	-
DQL26_RS06070 (NCTC8316_01218)	-	1208143..1209474 (-)	1332	WP_032460502.1	dipeptidase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37527.22 Da
• Isoelectric Point: 9.6692

>NTDB_id=1142843 DQL26_RS06045 WP_111693301.1 1203700..1204737(-) (sepM) [Streptococcus pyogenes strain NCTC8316]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRSVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=1142843 DQL26_RS06045 WP_111693301.1 1203700..1204737(-) (sepM) [Streptococcus pyogenes strain NCTC8316]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGTCTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGTGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGAGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-309)

• PDZ domain (PDZ_2) (129-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.565	100	0.696