Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   DQM63_RS03135 Genome accession   NZ_LS483385
Coordinates   604333..604995 (-) Length   220 a.a.
NCBI ID   WP_002900931.1    Uniprot ID   F2C7M4
Organism   Streptococcus sanguinis strain NCTC7863     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 599333..609995
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM63_RS03105 (NCTC7863_00608) - 599463..600026 (+) 564 WP_002913814.1 aminodeoxychorismate/anthranilate synthase component II -
  DQM63_RS03110 (NCTC7863_00609) trpD 600037..601041 (+) 1005 WP_002913813.1 anthranilate phosphoribosyltransferase -
  DQM63_RS03115 (NCTC7863_00610) trpC 601038..601805 (+) 768 WP_002913811.1 indole-3-glycerol phosphate synthase TrpC -
  DQM63_RS03120 (NCTC7863_00611) - 601792..602379 (+) 588 WP_002913809.1 phosphoribosylanthranilate isomerase -
  DQM63_RS03125 (NCTC7863_00612) trpB 602369..603592 (+) 1224 WP_002900933.1 tryptophan synthase subunit beta -
  DQM63_RS03130 (NCTC7863_00613) trpA 603585..604364 (+) 780 WP_002900932.1 tryptophan synthase subunit alpha -
  DQM63_RS03135 (NCTC7863_00614) cclA/cilC 604333..604995 (-) 663 WP_002900931.1 A24 family peptidase Machinery gene
  DQM63_RS03145 (NCTC7863_00615) - 605162..605677 (+) 516 WP_002900930.1 DNA starvation/stationary phase protection protein -
  DQM63_RS03150 (NCTC7863_00616) - 605769..605987 (+) 219 WP_002898045.1 YqgQ family protein -
  DQM63_RS03155 (NCTC7863_00617) - 605989..606369 (+) 381 WP_002900929.1 rhodanese-like domain-containing protein -
  DQM63_RS03160 (NCTC7863_00618) - 606459..606698 (+) 240 WP_002896181.1 DUF4190 domain-containing protein -
  DQM63_RS03165 (NCTC7863_00619) - 606731..607456 (-) 726 WP_002900928.1 pseudouridine synthase -
  DQM63_RS03170 (NCTC7863_00620) typA 607637..609484 (+) 1848 WP_002932699.1 translational GTPase TypA -
  DQM63_RS03175 (NCTC7863_00621) - 609508..609777 (+) 270 WP_002898040.1 DUF3165 family protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24978.27 Da        Isoelectric Point: 8.8759

>NTDB_id=1139621 DQM63_RS03135 WP_002900931.1 604333..604995(-) (cclA/cilC) [Streptococcus sanguinis strain NCTC7863]
MIHLYFFLIGTVFASFLGLVIDRFPERSIITPASHCNACGKRLAPRDLIPIFSQVMNRLRCRFCGDKIPLRYLFFEFILG
SLFLATSLGTISISQLLLLTMGLILAIYDQREQQYPLMVWLFFQLSLMMTTSVNPLMFFFLTLGLLAFFYNLHIGAGDFL
FLASCSAIFNLTEILLLIQIASFSGLACFCFKKKKDRLAFVPCLLFGVVVIISYKLLLLG

Nucleotide


Download         Length: 663 bp        

>NTDB_id=1139621 DQM63_RS03135 WP_002900931.1 604333..604995(-) (cclA/cilC) [Streptococcus sanguinis strain NCTC7863]
ATGATTCATCTATACTTTTTTCTTATTGGCACTGTCTTTGCCTCATTCCTAGGCTTGGTCATAGACCGCTTTCCAGAGCG
GTCTATCATCACTCCCGCTAGCCATTGCAATGCCTGCGGGAAAAGATTGGCTCCCCGTGATTTGATTCCTATTTTTTCTC
AAGTCATGAACCGTCTTCGTTGCCGCTTCTGTGGAGACAAGATTCCCTTACGCTATTTATTTTTTGAATTTATATTAGGC
AGTCTTTTTCTGGCAACTTCGCTTGGTACGATTTCCATCAGTCAACTTCTACTGCTCACTATGGGCTTGATCCTAGCCAT
CTACGATCAAAGAGAGCAGCAATACCCCTTGATGGTCTGGCTGTTTTTTCAGCTTTCGCTGATGATGACAACAAGTGTCA
ATCCTCTCATGTTCTTCTTTTTAACCCTAGGACTTCTAGCCTTCTTTTACAATCTCCATATCGGAGCTGGAGACTTTCTC
TTTCTGGCGTCCTGCTCAGCTATTTTCAATCTAACAGAAATTCTCCTTCTTATCCAAATCGCTAGCTTCTCTGGCCTCGC
CTGCTTCTGCTTTAAAAAGAAAAAAGACAGGCTAGCATTTGTACCTTGTCTTTTGTTTGGTGTGGTGGTGATTATTTCTT
ATAAGCTGCTGCTTCTTGGATAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-86)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F2C7M4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis NCTC 12261

57.991

99.545

0.577
  cclA/cilC Streptococcus mitis SK321

57.078

99.545

0.568
  cclA/cilC Streptococcus pneumoniae Rx1

56.164

99.545

0.559
  cclA/cilC Streptococcus pneumoniae D39

56.164

99.545

0.559
  cclA/cilC Streptococcus pneumoniae R6

56.164

99.545

0.559
  cclA/cilC Streptococcus pneumoniae TIGR4

55.708

99.545

0.555

Multiple sequence alignment