Detailed information NTG1137697

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: DQM73_RS03790
• Genome accession: NZ_LS483346
• Coordinates: 727657..728607 (+)
• Length: 316 a.a.
• NCBI ID: WP_002925450.1
• Uniprot ID: A0A2X3VL67
• Organism: Streptococcus sanguinis strain NCTC11085
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 722657..733607

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM73_RS03765 (NCTC11085_00731)	queA	722716..723744 (-)	1029	WP_002925457.1	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	-
DQM73_RS03770	-	723754..723933 (-)	180	WP_002897949.1	hypothetical protein	-
DQM73_RS03775 (NCTC11085_00732)	nagB	724068..724775 (+)	708	WP_002897948.1	glucosamine-6-phosphate deaminase	-
DQM73_RS03780 (NCTC11085_00733)	-	724926..726281 (+)	1356	WP_080561385.1	DUF1958 domain-containing protein	-
DQM73_RS03785 (NCTC11085_00734)	-	726376..727545 (+)	1170	WP_002925452.1	MFS transporter	-
DQM73_RS03790 (NCTC11085_00735)	coiA	727657..728607 (+)	951	WP_002925450.1	competence protein CoiA	Machinery gene
DQM73_RS03795 (NCTC11085_00736)	-	728763..729173 (+)	411	WP_002913758.1	DUF1310 family protein	-
DQM73_RS03800 (NCTC11085_00737)	-	729511..729918 (+)	408	WP_002913757.1	DUF1310 family protein	-
DQM73_RS03805 (NCTC11085_00738)	-	730071..730463 (+)	393	WP_002913753.1	DUF1310 family protein	-
DQM73_RS03810 (NCTC11085_00739)	-	730795..731181 (+)	387	WP_002913751.1	DUF1310 family protein	-
DQM73_RS03815 (NCTC11085_00740)	pepF	731377..733179 (+)	1803	WP_032908209.1	oligoendopeptidase F	Regulator

Sequence

Protein

• Length: 316 a.a.
• Molecular weight: 37573.32 Da
• Isoelectric Point: 7.8463

>NTDB_id=1137697 DQM73_RS03790 WP_002925450.1 727657..728607(+) (coiA) [Streptococcus sanguinis strain NCTC11085]
MFVARNHKGLLCNALEEKIEKGADFVCPACSGAVCFKKGKVMQPHFAHISLEECRFYRENESAEHLNLKAELFRWAIQTE
EVEVEAFLPALQQIADLLVDEKLALEVQCSPLSIERLQERTLSYRQHGYQVLWLLGRKLWLKDSLTRLQKDFLYFSKNMG
FHLWELDQEKRVLRLKYLIHEDLHGKVQHKTKTFPFGHGRLLDILRLPFQKQELNSFLAQQDLQICNYIRRQLYYQQPRW
MRLQAQLYQVGDNLLTKSAEDFYPQVRPIQAASFCQITTDLTDYYQQFENYYANLQQKNLQIVYSPAFYEMIREKC

Nucleotide

• Length: 951 bp

>NTDB_id=1137697 DQM73_RS03790 WP_002925450.1 727657..728607(+) (coiA) [Streptococcus sanguinis strain NCTC11085]
ATGTTTGTGGCGCGAAATCATAAGGGGCTTTTGTGTAATGCACTGGAGGAGAAGATTGAGAAAGGAGCCGATTTCGTCTG
CCCAGCTTGTTCAGGGGCAGTCTGTTTTAAAAAAGGGAAAGTTATGCAGCCGCATTTTGCGCATATTTCGCTAGAAGAGT
GTCGTTTTTATAGGGAAAATGAGAGCGCTGAGCACCTGAACCTTAAGGCGGAGCTTTTTCGCTGGGCTATCCAGACAGAA
GAAGTTGAGGTGGAGGCTTTTTTGCCTGCTCTGCAGCAGATTGCTGATCTACTGGTTGATGAAAAACTGGCGCTTGAAGT
CCAGTGCAGTCCCCTAAGTATAGAACGGCTGCAGGAACGGACGCTTTCTTACCGCCAGCATGGTTATCAGGTTCTCTGGC
TTTTGGGGCGAAAACTTTGGCTCAAGGATTCCCTAACTCGCCTGCAGAAGGATTTTCTCTATTTTAGTAAAAATATGGGC
TTTCATCTTTGGGAGCTGGATCAAGAAAAGCGAGTTCTGCGTCTCAAATACCTGATTCACGAAGATCTGCATGGAAAAGT
CCAGCACAAGACCAAGACCTTTCCCTTTGGTCACGGCCGTCTTTTGGATATTTTGCGTTTGCCCTTTCAAAAGCAGGAGT
TGAACAGTTTTCTGGCCCAGCAAGATCTGCAGATCTGCAATTATATACGCCGTCAGCTTTATTACCAGCAGCCTAGATGG
ATGCGGCTGCAGGCCCAACTCTATCAGGTTGGCGATAATCTCCTGACTAAGTCGGCAGAGGATTTCTATCCGCAGGTTAG
GCCGATACAGGCTGCCTCTTTCTGTCAGATAACTACTGACCTGACAGACTATTATCAGCAGTTTGAGAACTATTATGCCA
ATCTCCAGCAAAAAAATCTGCAAATTGTTTATTCACCGGCTTTTTATGAGATGATAAGAGAAAAATGCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (1-264)

3D structure

• AlphaFold DB: A0A2X3VL67

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus mitis NCTC 12261	55.161	98.101	0.541
coiA	Streptococcus pneumoniae TIGR4	53.871	98.101	0.528
coiA	Streptococcus pneumoniae Rx1	53.871	98.101	0.528
coiA	Streptococcus pneumoniae D39	53.871	98.101	0.528
coiA	Streptococcus pneumoniae R6	53.871	98.101	0.528
coiA	Lactococcus lactis subsp. cremoris KW2	42.769	100	0.44