Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   DQL34_RS01975 Genome accession   NZ_LS483339
Coordinates   366706..368223 (+) Length   505 a.a.
NCBI ID   WP_111679253.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain NCTC12958     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 361706..373223
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL34_RS11775 - 361986..362156 (+) 171 Protein_337 ascorbate 6-phosphate lactonase -
  DQL34_RS01950 (NCTC12958_00416) - 362173..362844 (-) 672 WP_064355629.1 potassium channel family protein -
  DQL34_RS01955 (NCTC12958_00417) - 362884..364248 (-) 1365 WP_111679249.1 TrkH family potassium uptake protein -
  DQL34_RS01960 (NCTC12958_00418) rsmG 364318..365031 (-) 714 WP_002949634.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  DQL34_RS01965 (NCTC12958_00419) - 365328..365864 (+) 537 WP_111679251.1 DUF177 domain-containing protein -
  DQL34_RS01970 (NCTC12958_00420) covR 366020..366709 (+) 690 WP_084828484.1 response regulator transcription factor Regulator
  DQL34_RS01975 (NCTC12958_00421) covS 366706..368223 (+) 1518 WP_111679253.1 HAMP domain-containing histidine kinase Regulator
  DQL34_RS01980 (NCTC12958_00422) nrdR 368346..368825 (+) 480 WP_002949642.1 transcriptional regulator NrdR -
  DQL34_RS01985 (NCTC12958_00423) - 368822..369997 (+) 1176 WP_111679255.1 DnaD domain protein -
  DQL34_RS01990 (NCTC12958_00424) dnaI 370001..370903 (+) 903 WP_084828487.1 primosomal protein DnaI -
  DQL34_RS01995 (NCTC12958_00425) der 371009..372319 (+) 1311 WP_084828488.1 ribosome biogenesis GTPase Der -
  DQL34_RS11275 - 372383..373051 (+) 669 Protein_348 HI_0552 family protein -

Sequence

Protein


Download         Length: 505 a.a.        Molecular weight: 57569.02 Da        Isoelectric Point: 5.3841

>NTDB_id=1137347 DQL34_RS01975 WP_111679253.1 366706..368223(+) (covS) [Streptococcus thermophilus strain NCTC12958]
MSKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSPEPLLAAFY
SPKNIYPSIINGVLSEKRSLDGQVAVSNRLYSNQSVYVYDKKGTFIFTSEEDTDSPPGMSEVNKLKLVSYKGKRGFLLQV
PIYGKDKKTIVGYAQVFHDLKFYYALKERLIFLLIFLEVGMTVLVIAVIVVVLTSILRPMRQLHETMGIIIDSPSDLELR
SKIESHDEIGALALNFNCMMDKIQEDNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHEANRM
TIMINDMLDSIRVKGSFDNHRNDTCDLNSSIRTVIGNFRVLHDDYQFYLNDSEGSDRPAQIYSQHFEQVITILIDNAVKY
SPVNKKIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCHIDVSSE
LGVGTRFDLYIPFAESETTTPQIEG

Nucleotide


Download         Length: 1518 bp        

>NTDB_id=1137347 DQL34_RS01975 WP_111679253.1 366706..368223(+) (covS) [Streptococcus thermophilus strain NCTC12958]
ATGAGTAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTTTCTTGTATTGTC
GATGTTCACTCTGGTTGTTGTATTTTCAGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAAATAATACAATCT
CAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCTGATGAAGAGTTGAGTCCAGAGCCGCTTTTAGCGGCCTTTTAT
TCACCGAAAAATATCTATCCATCAATCATTAATGGAGTGCTTTCTGAAAAGCGTTCCTTAGATGGTCAAGTTGCGGTTTC
TAATAGATTATATTCCAACCAGTCTGTCTATGTTTATGACAAAAAGGGAACTTTTATCTTTACTTCTGAGGAGGATACAG
ACTCACCTCCAGGCATGTCTGAGGTCAATAAACTGAAGTTGGTTTCCTATAAAGGTAAACGTGGTTTCTTACTACAAGTT
CCAATCTATGGCAAGGATAAGAAGACCATTGTTGGGTATGCTCAAGTTTTCCATGATTTGAAATTCTACTATGCGTTAAA
AGAGCGTTTAATTTTCCTATTGATATTCCTTGAAGTAGGAATGACGGTCTTAGTTATTGCAGTAATTGTAGTTGTCTTGA
CATCTATTCTTCGTCCGATGAGGCAGTTACACGAAACAATGGGTATTATTATCGATTCGCCAAGTGATTTGGAGCTTCGA
TCTAAGATTGAGAGTCATGATGAGATTGGTGCTTTGGCACTTAACTTTAACTGTATGATGGATAAAATTCAAGAAGATAA
TCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCACGAATTACGTACTCCCATTGCAGTTATTAAAGGACATATGGACC
TCTTGCAACGTTGGGGTAAAAATGATCCTGAAATCCTTGAAGAAAGTCTTGAAGCTGCAAGTCACGAAGCCAACCGTATG
ACGATTATGATTAACGATATGTTGGATTCTATTCGTGTTAAAGGGTCATTTGACAATCATAGAAATGATACATGTGATTT
GAATTCTTCAATCCGTACGGTTATTGGGAATTTCCGTGTCCTACATGACGACTACCAATTCTACCTCAATGATTCTGAGG
GTTCAGATCGTCCAGCACAGATTTACAGTCAGCACTTTGAACAGGTTATTACTATTTTGATTGATAATGCGGTCAAGTAT
TCGCCTGTTAATAAGAAAATCCAGGTTACTATCAAGGCTCTGGAAGATGAGATGCTGGTACAGGTACAGGATAATGGTGA
GGGTATCTCTAAAGAAGATATTGAACATATATTTGAACGCTTCTATCGTTCAGATAAGGCGCGTAATCGTACGACAACCC
AATCTGGTGTGGGTATTGGTTTATCAATCCTCTATCAAATTGTGGAAGCTTATCGATGCCATATCGATGTCAGTTCAGAA
CTTGGTGTGGGTACACGTTTTGACCTCTACATTCCTTTTGCAGAGTCAGAAACTACGACACCTCAAATTGAAGGTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(384-494)

His Kinase A (phospho-acceptor) domain (HisKA)

(270-329)

ArlS sensor domain (ArlS_N)

(39-187)

HAMP domain (HAMP)

(213-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

94.024

99.406

0.935

Multiple sequence alignment