Detailed information NTG1131326

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: H1X63_RS01605
• Genome accession: NZ_LR822027
• Coordinates: 293674..294573 (+)
• Length: 299 a.a.
• NCBI ID: WP_084825763.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_998
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	292328..293536	293674..294573	flank	138

Gene organization within MGE regions

Location: 292328..294573

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1X63_RS01600 (STHERMO_0294)	-	292328..293503 (-)	1176	WP_179972979.1	IS256-like element IS1191 family transposase	-
H1X63_RS01605 (STHERMO_0295)	comR	293674..294573 (+)	900	WP_084825763.1	helix-turn-helix domain-containing protein	Regulator

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35289.82 Da
• Isoelectric Point: 5.2314

>NTDB_id=1131326 H1X63_RS01605 WP_084825763.1 293674..294573(+) (comR) [Streptococcus thermophilus isolate STH_CIRM_998]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKKKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIVKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHKSFSDFLTVIDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=1131326 H1X63_RS01605 WP_084825763.1 293674..294573(+) (comR) [Streptococcus thermophilus isolate STH_CIRM_998]
TTGAACATAAAAGACAGCATTGGATTAAGAATCAAAACTGAGCGTGAACGGCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCATCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAGGTTGAGGAAATATACGAGGACTTGTTTGAACAAGTCAAAAAGAAGAGGAAGTTCTCGACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TGTAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCATAAGTCCTTCTCAGACTTCTTAACAGTTATAGATAAAGCATTAGCTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	98.662	100	0.987
comR	Streptococcus thermophilus LMD-9	97.993	100	0.98
comR	Streptococcus salivarius strain HSISS4	94.649	100	0.946
comR	Streptococcus salivarius SK126	93.98	100	0.94
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	42.475	100	0.425
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.475	100	0.425