Detailed information
Bioinformatically predicted
Overview
| Name | vicX | Type | Regulator |
| Locus tag | H1X08_RS04540 | Genome accession | NZ_LR822025 |
| Coordinates | 891714..892526 (+) | Length | 270 a.a. |
| NCBI ID | WP_179971933.1 | Uniprot ID | - |
| Organism | Streptococcus thermophilus isolate STH_CIRM_961 | ||
| Function | require for competence development (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 864622..904426 | 891714..892526 | within | 0 |
Gene organization within MGE regions
Location: 864622..904426
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H1X08_RS10670 | - | 865602..865778 (-) | 177 | WP_232086976.1 | tyrosine-type recombinase/integrase | - |
| H1X08_RS04380 (STHERMO_0978) | - | 865906..866643 (-) | 738 | WP_232086965.1 | Arm DNA-binding domain-containing protein | - |
| H1X08_RS04385 (STHERMO_0979) | - | 866748..867359 (-) | 612 | WP_232086966.1 | CD20-like domain-containing protein | - |
| H1X08_RS04390 (STHERMO_0980) | - | 867443..867811 (-) | 369 | WP_180482594.1 | ImmA/IrrE family metallo-endopeptidase | - |
| H1X08_RS04395 (STHERMO_0982) | - | 868057..868938 (-) | 882 | WP_180482595.1 | hypothetical protein | - |
| H1X08_RS04400 (STHERMO_0983) | - | 868941..869291 (-) | 351 | WP_180482596.1 | helix-turn-helix domain-containing protein | - |
| H1X08_RS04405 (STHERMO_0984) | - | 869598..869807 (+) | 210 | WP_180482597.1 | helix-turn-helix domain-containing protein | - |
| H1X08_RS04410 | - | 869820..870014 (+) | 195 | WP_180482598.1 | hypothetical protein | - |
| H1X08_RS04415 (STHERMO_0987) | - | 870410..870586 (-) | 177 | WP_014727550.1 | DUF3042 family protein | - |
| H1X08_RS04420 (STHERMO_0988) | miaA | 870663..871562 (+) | 900 | WP_179971952.1 | tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA | - |
| H1X08_RS04425 (STHERMO_0989) | - | 871607..872107 (+) | 501 | WP_171815269.1 | GAF domain-containing protein | - |
| H1X08_RS04430 (STHERMO_0990) | dnaX | 872107..873759 (+) | 1653 | WP_179971950.1 | DNA polymerase III subunit gamma/tau | - |
| H1X08_RS04435 (STHERMO_0991) | - | 873898..874083 (+) | 186 | WP_011681224.1 | DUF3272 family protein | - |
| H1X08_RS04440 (STHERMO_0992) | birA | 874070..875008 (-) | 939 | WP_011681223.1 | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | - |
| H1X08_RS04445 (STHERMO_0993) | metK | 875288..876481 (+) | 1194 | WP_180482599.1 | methionine adenosyltransferase | - |
| H1X08_RS04450 (STHERMO_0994) | - | 877505..877960 (+) | 456 | WP_180482600.1 | DUF4832 domain-containing protein | - |
| H1X08_RS04455 (STHERMO_0995) | galE | 877975..878988 (+) | 1014 | WP_180482601.1 | UDP-glucose 4-epimerase GalE | - |
| H1X08_RS04460 (STHERMO_0996) | - | 879176..879412 (+) | 237 | WP_002946959.1 | DUF1146 family protein | - |
| H1X08_RS04465 (STHERMO_0997) | murA | 879480..880751 (+) | 1272 | WP_180482602.1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | - |
| H1X08_RS04470 (STHERMO_0998) | - | 880753..880941 (+) | 189 | WP_011226090.1 | DNA-directed RNA polymerase subunit beta | - |
| H1X08_RS04475 (STHERMO_0999) | endA | 881003..881884 (+) | 882 | WP_084828863.1 | DNA/RNA non-specific endonuclease | Machinery gene |
| H1X08_RS10675 (STHERMO_1001) | - | 882059..883316 (+) | 1258 | Protein_851 | ISL3 family transposase | - |
| H1X08_RS04490 | - | 883445..883972 (-) | 528 | WP_179971942.1 | HdeD family acid-resistance protein | - |
| H1X08_RS11375 | - | 884025..884183 (-) | 159 | WP_179973363.1 | hypothetical protein | - |
| H1X08_RS04500 (STHERMO_1005) | - | 884226..884702 (+) | 477 | WP_179971941.1 | transposase | - |
| H1X08_RS04505 (STHERMO_1007) | - | 884834..886090 (+) | 1257 | Protein_855 | ISL3 family transposase | - |
| H1X08_RS04510 (STHERMO_1009) | - | 886154..886804 (-) | 651 | WP_179971939.1 | amino acid ABC transporter permease | - |
| H1X08_RS04515 (STHERMO_1010) | - | 886816..887514 (-) | 699 | WP_179971938.1 | amino acid ABC transporter permease | - |
| H1X08_RS04520 (STHERMO_1011) | - | 887532..888365 (-) | 834 | WP_180482603.1 | transporter substrate-binding domain-containing protein | - |
| H1X08_RS04525 (STHERMO_1012) | - | 888377..889144 (-) | 768 | WP_180482604.1 | amino acid ABC transporter ATP-binding protein | - |
| H1X08_RS04530 (STHERMO_1014) | vicR | 889668..890375 (+) | 708 | WP_179971935.1 | response regulator YycF | Regulator |
| H1X08_RS04535 (STHERMO_1015) | vicK | 890368..891708 (+) | 1341 | WP_179971934.1 | cell wall metabolism sensor histidine kinase VicK | Regulator |
| H1X08_RS04540 (STHERMO_1016) | vicX | 891714..892526 (+) | 813 | WP_179971933.1 | MBL fold metallo-hydrolase | Regulator |
| H1X08_RS04545 (STHERMO_1017) | - | 892586..892947 (+) | 362 | Protein_863 | YbaN family protein | - |
| H1X08_RS04550 (STHERMO_1018) | - | 893000..894214 (-) | 1215 | WP_179973777.1 | aminoacyltransferase | - |
| H1X08_RS04555 (STHERMO_1019) | yidA | 894216..895025 (-) | 810 | WP_179971931.1 | sugar-phosphatase | - |
| H1X08_RS04560 | - | 895233..896097 (+) | 865 | Protein_866 | GNAT family N-acetyltransferase | - |
| H1X08_RS04565 (STHERMO_1022) | - | 896189..896575 (+) | 387 | WP_002953113.1 | DUF1934 domain-containing protein | - |
| H1X08_RS04570 (STHERMO_1023) | - | 896867..899551 (+) | 2685 | WP_179971930.1 | calcium-translocating P-type ATPase, PMCA-type | - |
| H1X08_RS04575 (STHERMO_1024) | - | 899656..900402 (+) | 747 | WP_179971929.1 | NADPH-dependent oxidoreductase | - |
| H1X08_RS04580 (STHERMO_1025) | - | 900426..901283 (-) | 858 | WP_023909690.1 | metallophosphoesterase | - |
| H1X08_RS04585 (STHERMO_1026) | queG | 901377..902495 (+) | 1119 | WP_179971928.1 | tRNA epoxyqueuosine(34) reductase QueG | - |
| H1X08_RS04590 (STHERMO_1027) | prfB | 902548..903649 (+) | 1102 | WP_180482605.1 | peptide chain release factor 2 | - |
| H1X08_RS04595 (STHERMO_1028) | ftsE | 903734..904426 (+) | 693 | WP_179973007.1 | cell division ATP-binding protein FtsE | - |
Sequence
Protein
Download Length: 270 a.a. Molecular weight: 30116.13 Da Isoelectric Point: 5.7792
>NTDB_id=1131209 H1X08_RS04540 WP_179971933.1 891714..892526(+) (vicX) [Streptococcus thermophilus isolate STH_CIRM_961]
MTLELGFKYSILASGSTGNSFYLETPEKKILVDAGLSGKKITSLLAEIDRDPSDLDAILITHEHKDHIHGVGVLARKYGM
DIYANEKTWQIMDSKNMLGKVNNSQKHVFSRDKLLTFGDIDIESFGVSHDAIDPQFYRFMKDGKSFVMLTDTGYVSDRMA
GLIENADGYLIESNHDVEILRAGSYPWSTKQRILSDQGHLCNEDGADAMIRTIGNKTKKIYLGHLSKENNIKELAHMTME
NQLARADFGVGTDFKIFGTSPDTVTPLTDI
MTLELGFKYSILASGSTGNSFYLETPEKKILVDAGLSGKKITSLLAEIDRDPSDLDAILITHEHKDHIHGVGVLARKYGM
DIYANEKTWQIMDSKNMLGKVNNSQKHVFSRDKLLTFGDIDIESFGVSHDAIDPQFYRFMKDGKSFVMLTDTGYVSDRMA
GLIENADGYLIESNHDVEILRAGSYPWSTKQRILSDQGHLCNEDGADAMIRTIGNKTKKIYLGHLSKENNIKELAHMTME
NQLARADFGVGTDFKIFGTSPDTVTPLTDI
Nucleotide
Download Length: 813 bp
>NTDB_id=1131209 H1X08_RS04540 WP_179971933.1 891714..892526(+) (vicX) [Streptococcus thermophilus isolate STH_CIRM_961]
ATGACCTTAGAATTAGGGTTTAAATATAGTATTTTGGCTTCAGGGTCAACCGGGAATTCCTTTTATTTGGAAACTCCAGA
AAAGAAGATTCTAGTGGATGCTGGTTTATCAGGAAAAAAAATTACGAGTTTGCTAGCGGAGATTGACCGCGATCCAAGTG
ATCTTGATGCTATCTTAATAACGCATGAACACAAGGACCATATCCATGGTGTAGGTGTTTTAGCTCGTAAATACGGCATG
GATATCTACGCCAATGAGAAAACCTGGCAAATTATGGATAGTAAGAATATGCTAGGTAAGGTTAATAATAGTCAGAAACA
TGTTTTTTCTCGCGATAAGCTTCTAACCTTTGGTGATATCGACATTGAATCTTTCGGAGTTAGTCATGATGCCATTGATC
CACAATTTTACCGCTTTATGAAAGACGGAAAGAGCTTTGTCATGTTGACGGATACAGGCTATGTTTCAGACCGTATGGCG
GGTCTTATTGAAAATGCTGATGGCTATCTGATTGAATCTAATCATGATGTTGAAATCTTGAGAGCAGGTTCTTATCCTTG
GTCAACCAAGCAACGTATCCTCTCTGATCAGGGTCACTTGTGTAATGAGGATGGAGCCGATGCTATGATTCGTACCATCG
GTAATAAAACTAAAAAGATTTATCTGGGTCACCTTTCCAAAGAAAATAATATCAAGGAATTGGCCCACATGACGATGGAA
AATCAGCTGGCTCGCGCTGACTTTGGTGTTGGAACTGACTTTAAGATTTTTGGTACCTCACCAGATACGGTGACCCCACT
AACAGATATTTAG
ATGACCTTAGAATTAGGGTTTAAATATAGTATTTTGGCTTCAGGGTCAACCGGGAATTCCTTTTATTTGGAAACTCCAGA
AAAGAAGATTCTAGTGGATGCTGGTTTATCAGGAAAAAAAATTACGAGTTTGCTAGCGGAGATTGACCGCGATCCAAGTG
ATCTTGATGCTATCTTAATAACGCATGAACACAAGGACCATATCCATGGTGTAGGTGTTTTAGCTCGTAAATACGGCATG
GATATCTACGCCAATGAGAAAACCTGGCAAATTATGGATAGTAAGAATATGCTAGGTAAGGTTAATAATAGTCAGAAACA
TGTTTTTTCTCGCGATAAGCTTCTAACCTTTGGTGATATCGACATTGAATCTTTCGGAGTTAGTCATGATGCCATTGATC
CACAATTTTACCGCTTTATGAAAGACGGAAAGAGCTTTGTCATGTTGACGGATACAGGCTATGTTTCAGACCGTATGGCG
GGTCTTATTGAAAATGCTGATGGCTATCTGATTGAATCTAATCATGATGTTGAAATCTTGAGAGCAGGTTCTTATCCTTG
GTCAACCAAGCAACGTATCCTCTCTGATCAGGGTCACTTGTGTAATGAGGATGGAGCCGATGCTATGATTCGTACCATCG
GTAATAAAACTAAAAAGATTTATCTGGGTCACCTTTCCAAAGAAAATAATATCAAGGAATTGGCCCACATGACGATGGAA
AATCAGCTGGCTCGCGCTGACTTTGGTGTTGGAACTGACTTTAAGATTTTTGGTACCTCACCAGATACGGTGACCCCACT
AACAGATATTTAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| vicX | Streptococcus mutans UA159 |
76.404 |
98.889 |
0.756 |