Detailed information NTG1128124

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: FGL17_RS02600
• Genome accession: NZ_LR594052
• Coordinates: 503181..504224 (+)
• Length: 347 a.a.
• NCBI ID: WP_003082628.1
• Uniprot ID: A0A4V0GZT7
• Organism: Streptococcus porcinus strain NCTC10924
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 498181..509224

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL17_RS02575 (NCTC10924_00519)	-	498603..499934 (+)	1332	WP_138083605.1	dipeptidase	-
FGL17_RS02580 (NCTC10924_00520)	arcC	499951..500901 (+)	951	WP_003082752.1	carbamate kinase	-
FGL17_RS02585 (NCTC10924_00521)	asnA	501080..502072 (+)	993	WP_093958900.1	aspartate--ammonia ligase	-
FGL17_RS02590 (NCTC10924_00522)	rsmD	502174..502713 (+)	540	WP_093958899.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
FGL17_RS02595 (NCTC10924_00523)	coaD	502703..503194 (+)	492	WP_093958898.1	pantetheine-phosphate adenylyltransferase	-
FGL17_RS02600 (NCTC10924_00524)	sepM	503181..504224 (+)	1044	WP_003082628.1	SepM family pheromone-processing serine protease	Regulator
FGL17_RS02605 (NCTC10924_00525)	-	504354..506309 (+)	1956	WP_003084642.1	BglG family transcription antiterminator	-
FGL17_RS02610 (NCTC10924_00526)	-	506337..506810 (+)	474	WP_039985002.1	PTS sugar transporter subunit IIA	-
FGL17_RS02615 (NCTC10924_00527)	-	506812..507090 (+)	279	WP_003083266.1	PTS sugar transporter subunit IIB	-
FGL17_RS02620 (NCTC10924_00528)	-	507102..508442 (+)	1341	WP_003085397.1	PTS galactitol transporter subunit IIC	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 38318.33 Da
• Isoelectric Point: 10.1692

>NTDB_id=1128124 FGL17_RS02600 WP_003082628.1 503181..504224(+) (sepM) [Streptococcus porcinus strain NCTC10924]
MKIIKKVKWWLISILAVVALLFALFFPLPYYIEMPGGAYDIRSVLQINNKKDKEKGSYNFVAVSLSRATFAQILYAWVTP
FTEISSVENTTGGYSAADYMRINQYYMETSQNGAIYQALKLAGKPVSLDYLGVYVLDVNKDSTFRGVLNIADTVTGVNKK
EFKSSADLIKYVSSLKRGEQVTVQYTTGNEKRSKSGKVIKLKNGKNGIGIGLTDHTKVHTDEKIEFSTEGVGGPSAGLMF
TLDIYDQLNQENLRKGRRIAGTGTIDQDGKVGDIGGAGLKVVAAAKEGAEIFFVPNNPVDKRIKKVKPNAKTNYKEALDV
AKKLKTKMKIVPVRNVKEAIAYLQKTE

Nucleotide

• Length: 1044 bp

>NTDB_id=1128124 FGL17_RS02600 WP_003082628.1 503181..504224(+) (sepM) [Streptococcus porcinus strain NCTC10924]
ATGAAGATAATTAAAAAAGTCAAATGGTGGTTAATTAGTATTCTGGCAGTAGTTGCCCTCTTATTTGCCCTCTTTTTCCC
TTTACCTTATTATATTGAGATGCCTGGCGGCGCTTACGATATTCGTTCAGTACTCCAGATAAACAATAAGAAGGATAAGG
AAAAAGGCTCTTACAATTTTGTAGCAGTTAGTTTGAGTCGAGCTACCTTTGCGCAAATCCTTTATGCTTGGGTAACGCCA
TTTACAGAGATTTCATCTGTAGAAAATACAACTGGTGGTTACAGTGCGGCAGATTATATGCGTATAAATCAATATTACAT
GGAGACCTCTCAAAATGGAGCTATCTACCAAGCTTTAAAATTAGCTGGAAAACCTGTTTCATTAGACTATTTAGGTGTTT
ATGTTTTGGATGTTAATAAAGATTCAACTTTTCGTGGTGTTTTAAATATTGCAGATACAGTTACAGGAGTCAATAAAAAG
GAATTTAAAAGTTCAGCTGATCTCATTAAGTACGTTTCAAGTTTGAAACGAGGTGAACAGGTCACGGTTCAATATACTAC
TGGTAATGAGAAAAGATCCAAAAGTGGTAAGGTCATTAAGCTAAAAAACGGTAAAAATGGTATTGGTATTGGTTTAACAG
ACCACACAAAAGTACATACAGACGAAAAAATTGAGTTTTCAACAGAAGGTGTAGGTGGGCCAAGTGCTGGACTTATGTTT
ACACTGGATATTTATGATCAACTGAATCAAGAAAATCTGCGTAAAGGTCGTCGTATTGCAGGTACTGGAACAATTGATCA
AGATGGTAAAGTTGGTGATATTGGTGGTGCAGGTTTAAAAGTCGTGGCTGCAGCCAAGGAAGGTGCAGAGATTTTCTTCG
TGCCTAATAACCCAGTTGATAAGCGTATCAAAAAAGTGAAGCCAAATGCAAAGACCAATTACAAAGAGGCCTTAGATGTA
GCAAAAAAATTAAAAACCAAGATGAAAATCGTCCCAGTTAGAAATGTTAAAGAAGCTATTGCTTATTTGCAAAAGACTGA
ATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (131-192)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-340)

3D structure

• AlphaFold DB: A0A4V0GZT7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	71.304	99.424	0.709