Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   FGK94_RS01670 Genome accession   NZ_LR590471
Coordinates   366165..367475 (-) Length   436 a.a.
NCBI ID   WP_012515549.1    Uniprot ID   A0AAW3GN95
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC11854     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 361165..372475
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK94_RS01630 (NCTC11854_00344) rpsT 361500..361748 (+) 249 WP_012678006.1 30S ribosomal protein S20 -
  FGK94_RS01635 (NCTC11854_00345) - 361961..362245 (-) 285 WP_042670597.1 hypothetical protein -
  FGK94_RS01640 (NCTC11854_00346) - 362264..362656 (-) 393 WP_042670596.1 hypothetical protein -
  FGK94_RS01645 (NCTC11854_00347) - 362653..363846 (-) 1194 WP_024273226.1 lipase -
  FGK94_RS01650 (NCTC11854_00348) - 363847..364260 (-) 414 WP_037584321.1 hypothetical protein -
  FGK94_RS01655 (NCTC11854_00349) - 364276..364536 (-) 261 WP_021320716.1 hypothetical protein -
  FGK94_RS01660 (NCTC11854_00350) - 364533..364913 (-) 381 WP_043029682.1 hypothetical protein -
  FGK94_RS10265 (NCTC11854_00351) - 365088..365264 (-) 177 WP_195757361.1 hypothetical protein -
  FGK94_RS01665 (NCTC11854_00352) - 365346..365780 (-) 435 WP_012678015.1 hypothetical protein -
  FGK94_RS01670 (NCTC11854_00353) ciaH 366165..367475 (-) 1311 WP_012515549.1 sensor histidine kinase Regulator
  FGK94_RS01675 (NCTC11854_00354) ciaR 367468..368142 (-) 675 WP_012515548.1 response regulator transcription factor Regulator
  FGK94_RS01680 (NCTC11854_00355) - 368561..371098 (-) 2538 WP_043029677.1 M1 family metallopeptidase -
  FGK94_RS01685 (NCTC11854_00356) phoU 371332..371985 (-) 654 WP_012678018.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49574.22 Da        Isoelectric Point: 9.6507

>NTDB_id=1126856 FGK94_RS01670 WP_012515549.1 366165..367475(-) (ciaH) [Streptococcus equi subsp. zooepidemicus strain NCTC11854]
MNKLKKGLLSDNYTHFFHFFAIFTGIFVVMTIIILQIMRFSVYSTVDSSLISVGQNASNYANRTMARISSFYFDAENNLI
QALPELEASKSLGSSTTNMDIILFSANGTILNSFDAFSNYQSFRLDKSQLNNIVTTQLMNFYGQKEKYHTLTVKVHIKNY
PAVAYMMAVVNVQQLDTANERYEQIIIMVMIVFWLISILASIYLAKWSRKPIMESYAKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILDNSEHIASSLDEVRNMRILTTNLLNLARRDDGIKPQLVDVDAAFFDTVFENYQLVAEESGKQFISAN
QINRPLKTDKALLKQLMTILFDNAIKYTDHNGVVEVKVRTTDKHLLISVIDNGPGIKDDDKKKIFDRFYRVDKARTRQKG
GFGLGLALAQQIVTSLKGTITVSDNKPTGAIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=1126856 FGK94_RS01670 WP_012515549.1 366165..367475(-) (ciaH) [Streptococcus equi subsp. zooepidemicus strain NCTC11854]
ATGAATAAACTAAAAAAAGGATTATTGTCCGATAATTATACGCATTTTTTTCATTTCTTTGCTATTTTTACAGGCATTTT
TGTTGTCATGACCATCATTATTTTGCAAATCATGAGGTTTAGTGTCTATTCCACAGTAGACAGCAGTCTCATTTCGGTCG
GTCAAAATGCCAGTAACTATGCCAATAGGACCATGGCGAGAATATCTTCCTTTTATTTTGATGCAGAAAATAACCTTATT
CAGGCTCTTCCTGAACTGGAAGCGTCAAAATCACTTGGCTCCTCCACCACTAATATGGATATTATTTTATTTAGTGCTAA
TGGGACGATATTGAACTCCTTTGACGCTTTCTCTAATTACCAAAGCTTTCGTTTAGACAAAAGCCAGCTCAATAACATTG
TCACAACACAGCTGATGAATTTTTATGGGCAAAAGGAGAAATACCATACCCTAACTGTTAAGGTTCACATTAAAAACTAT
CCAGCAGTGGCTTATATGATGGCAGTGGTTAATGTTCAGCAGTTGGATACTGCTAATGAGCGCTATGAACAGATTATTAT
CATGGTTATGATTGTCTTTTGGTTAATTTCGATTTTAGCCAGTATTTATTTGGCTAAGTGGAGCAGAAAGCCAATTATGG
AGAGCTATGCTAAGCAAAAAATGTTTGTAGAAAATGCCAGTCATGAGCTTAGGACTCCTTTAGCGGTGCTGCAAAATCGT
TTGGAATCGCTGTTTAGAAAGCCTAACGAAACCATTTTAGACAATAGCGAGCATATTGCGTCAAGCCTAGATGAGGTTCG
TAATATGAGAATATTAACAACTAATCTGTTAAATTTAGCCAGACGTGATGATGGGATCAAGCCGCAGCTAGTTGATGTTG
ATGCAGCATTTTTTGACACTGTTTTTGAAAATTATCAATTAGTTGCAGAAGAATCAGGCAAGCAGTTTATCTCAGCTAAT
CAGATCAATAGGCCCTTAAAGACGGATAAGGCTTTGCTCAAGCAGCTGATGACCATTTTGTTTGATAATGCGATCAAATA
CACTGATCATAACGGTGTGGTTGAGGTCAAGGTTAGAACGACCGATAAGCATTTATTGATTTCTGTTATTGATAATGGCC
CAGGGATCAAGGATGATGATAAGAAAAAGATTTTTGATCGCTTTTACCGAGTGGATAAGGCAAGGACACGCCAAAAAGGA
GGCTTTGGACTCGGATTGGCCTTAGCGCAGCAGATCGTTACCTCATTAAAAGGAACGATTACCGTCAGTGATAATAAGCC
TACCGGCGCCATCTTTGAAGTAAAATTATAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.895

100

0.58
  ciaH Streptococcus pneumoniae Rx1

51.376

100

0.514
  ciaH Streptococcus pneumoniae D39

51.376

100

0.514
  ciaH Streptococcus pneumoniae R6

51.376

100

0.514
  ciaH Streptococcus pneumoniae TIGR4

51.376

100

0.514

Multiple sequence alignment