Detailed information
Bioinformatically predicted
Overview
| Name | radA | Type | Machinery gene |
| Locus tag | FGK81_RS08375 | Genome accession | NZ_LR590466 |
| Coordinates | 1634129..1635490 (-) | Length | 453 a.a. |
| NCBI ID | WP_002986109.1 | Uniprot ID | A0A4Q1R665 |
| Organism | Streptococcus pyogenes strain NCTC8193 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1635571..1699457 | 1634129..1635490 | flank | 81 |
Gene organization within MGE regions
Location: 1634129..1699457
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FGK81_RS08375 (NCTC8193_01662) | radA | 1634129..1635490 (-) | 1362 | WP_002986109.1 | DNA repair protein RadA | Machinery gene |
| FGK81_RS08380 (NCTC8193_01663) | - | 1635571..1636017 (-) | 447 | WP_002986111.1 | dUTP diphosphatase | - |
| FGK81_RS08385 (NCTC8193_01664) | - | 1636127..1636894 (-) | 768 | WP_002986113.1 | epoxyqueuosine reductase QueH | - |
| FGK81_RS08390 (NCTC8193_01665) | - | 1637012..1638796 (-) | 1785 | WP_011888576.1 | ABC transporter ATP-binding protein | - |
| FGK81_RS08395 (NCTC8193_01666) | - | 1638799..1640505 (-) | 1707 | WP_011888575.1 | ABC transporter ATP-binding protein | - |
| FGK81_RS08400 (NCTC8193_01667) | - | 1640498..1640947 (-) | 450 | WP_002986120.1 | MarR family winged helix-turn-helix transcriptional regulator | - |
| FGK81_RS08405 (NCTC8193_01668) | - | 1641245..1642261 (+) | 1017 | WP_002986123.1 | NAD(P)H-dependent glycerol-3-phosphate dehydrogenase | - |
| FGK81_RS08410 (NCTC8193_01669) | galU | 1642294..1643193 (+) | 900 | WP_002986125.1 | UTP--glucose-1-phosphate uridylyltransferase GalU | - |
| FGK81_RS08415 (NCTC8193_01670) | - | 1643292..1643963 (-) | 672 | WP_011017305.1 | rhomboid family intramembrane serine protease | - |
| FGK81_RS08420 | - | 1644651..1646159 (+) | 1509 | WP_023077512.1 | helix-turn-helix domain-containing protein | - |
| FGK81_RS08425 (NCTC8193_01673) | - | 1646507..1647856 (-) | 1350 | WP_011888573.1 | glucose-6-phosphate isomerase | - |
| FGK81_RS08430 (NCTC8193_01674) | speG | 1648312..1649022 (-) | 711 | WP_038433795.1 | streptococcal pyrogenic exotoxin SpeG | - |
| FGK81_RS08435 (NCTC8193_01675) | - | 1649108..1650106 (+) | 999 | WP_011888572.1 | IS30-like element IS1239 family transposase | - |
| FGK81_RS08440 (NCTC8193_01677) | - | 1650777..1650968 (+) | 192 | WP_002986145.1 | helix-turn-helix domain-containing protein | - |
| FGK81_RS08445 (NCTC8193_01678) | prx | 1651018..1651200 (-) | 183 | WP_002986147.1 | hypothetical protein | Regulator |
| FGK81_RS08450 (NCTC8193_01679) | sda1 | 1651439..1652611 (+) | 1173 | WP_032467302.1 | streptodornase Sda1 | - |
| FGK81_RS08455 (NCTC8193_01680) | - | 1652727..1653932 (-) | 1206 | WP_002986150.1 | glucosaminidase domain-containing protein | - |
| FGK81_RS08460 (NCTC8193_01682) | - | 1654044..1654499 (-) | 456 | WP_002986151.1 | phage holin family protein | - |
| FGK81_RS08465 (NCTC8193_01683) | - | 1654509..1655126 (-) | 618 | WP_111713133.1 | DUF1366 domain-containing protein | - |
| FGK81_RS08470 (NCTC8193_01684) | - | 1655129..1655560 (-) | 432 | WP_002987513.1 | DUF1617 family protein | - |
| FGK81_RS08475 (NCTC8193_01685) | - | 1655572..1657587 (-) | 2016 | WP_138060167.1 | gp58-like family protein | - |
| FGK81_RS08480 (NCTC8193_01686) | hylP | 1657603..1658619 (-) | 1017 | WP_111690640.1 | hyaluronidase HylP | - |
| FGK81_RS08485 (NCTC8193_01687) | - | 1658619..1660625 (-) | 2007 | WP_171004415.1 | phage tail spike protein | - |
| FGK81_RS08490 (NCTC8193_01688) | - | 1660664..1661371 (-) | 708 | WP_111680754.1 | phage tail domain-containing protein | - |
| FGK81_RS08495 (NCTC8193_01689) | - | 1661371..1664772 (-) | 3402 | WP_138060168.1 | phage tail tape measure protein | - |
| FGK81_RS09865 (NCTC8193_01690) | - | 1664846..1665004 (-) | 159 | WP_002986162.1 | hypothetical protein | - |
| FGK81_RS08500 (NCTC8193_01691) | - | 1665040..1665411 (-) | 372 | WP_002986164.1 | hypothetical protein | - |
| FGK81_RS08505 (NCTC8193_01692) | - | 1665432..1666019 (-) | 588 | WP_002986166.1 | hypothetical protein | - |
| FGK81_RS08510 (NCTC8193_01693) | - | 1666030..1666452 (-) | 423 | WP_002986168.1 | hypothetical protein | - |
| FGK81_RS08515 (NCTC8193_01694) | - | 1666461..1666832 (-) | 372 | WP_002986170.1 | hypothetical protein | - |
| FGK81_RS08520 (NCTC8193_01695) | - | 1666804..1667181 (-) | 378 | WP_111680753.1 | phage head-tail adapter protein | - |
| FGK81_RS08525 (NCTC8193_01696) | - | 1667183..1667476 (-) | 294 | WP_002986174.1 | phage gp6-like head-tail connector protein | - |
| FGK81_RS08530 (NCTC8193_01697) | - | 1667496..1667783 (-) | 288 | WP_002986176.1 | hypothetical protein | - |
| FGK81_RS08535 (NCTC8193_01698) | - | 1667798..1668991 (-) | 1194 | WP_002986177.1 | phage major capsid protein | - |
| FGK81_RS08540 (NCTC8193_01699) | - | 1669027..1669743 (-) | 717 | WP_002986180.1 | head maturation protease, ClpP-related | - |
| FGK81_RS08545 (NCTC8193_01700) | - | 1669747..1670982 (-) | 1236 | WP_002986182.1 | phage portal protein | - |
| FGK81_RS08550 (NCTC8193_01701) | - | 1671181..1672839 (-) | 1659 | WP_002986185.1 | terminase TerL endonuclease subunit | - |
| FGK81_RS08555 (NCTC8193_01702) | - | 1672820..1673167 (-) | 348 | WP_002986187.1 | hypothetical protein | - |
| FGK81_RS08560 (NCTC8193_01703) | - | 1673289..1673618 (-) | 330 | WP_002986189.1 | HNH endonuclease | - |
| FGK81_RS08565 (NCTC8193_01704) | - | 1673615..1673908 (-) | 294 | WP_002986191.1 | hypothetical protein | - |
| FGK81_RS08570 (NCTC8193_01705) | - | 1674080..1674643 (-) | 564 | WP_032467304.1 | site-specific integrase | - |
| FGK81_RS08575 (NCTC8193_01706) | - | 1674738..1675157 (-) | 420 | WP_002986196.1 | DUF1492 domain-containing protein | - |
| FGK81_RS08580 (NCTC8193_01707) | - | 1675181..1675381 (-) | 201 | WP_002986198.1 | hypothetical protein | - |
| FGK81_RS09870 (NCTC8193_01708) | - | 1675350..1675499 (-) | 150 | WP_002986201.1 | hypothetical protein | - |
| FGK81_RS08590 (NCTC8193_01710) | - | 1675684..1675932 (-) | 249 | WP_002986206.1 | hypothetical protein | - |
| FGK81_RS09875 (NCTC8193_01711) | - | 1675935..1676108 (-) | 174 | WP_002986209.1 | hypothetical protein | - |
| FGK81_RS08595 (NCTC8193_01712) | - | 1676105..1676434 (-) | 330 | WP_002986212.1 | helix-turn-helix domain-containing protein | - |
| FGK81_RS08600 (NCTC8193_01713) | - | 1676427..1676759 (-) | 333 | WP_002986215.1 | hypothetical protein | - |
| FGK81_RS09925 | - | 1676752..1676925 (-) | 174 | Protein_1642 | DUF3310 domain-containing protein | - |
| FGK81_RS09930 (NCTC8193_01714) | - | 1677079..1677351 (-) | 273 | Protein_1643 | hypothetical protein | - |
| FGK81_RS09935 (NCTC8193_01715) | - | 1677341..1677580 (-) | 240 | WP_002986221.1 | DNA cytosine methyltransferase | - |
| FGK81_RS09940 | - | 1677587..1677805 (-) | 219 | WP_002986224.1 | hypothetical protein | - |
| FGK81_RS09885 (NCTC8193_01716) | - | 1677786..1677941 (-) | 156 | WP_002986227.1 | hypothetical protein | - |
| FGK81_RS08620 (NCTC8193_01717) | - | 1677929..1678567 (-) | 639 | WP_050452837.1 | DNA cytosine methyltransferase | - |
| FGK81_RS08625 (NCTC8193_01718) | - | 1678570..1678854 (-) | 285 | WP_002986233.1 | hypothetical protein | - |
| FGK81_RS08630 (NCTC8193_01719) | - | 1678851..1679051 (-) | 201 | WP_002986235.1 | hypothetical protein | - |
| FGK81_RS08635 (NCTC8193_01720) | - | 1679041..1679268 (-) | 228 | WP_002986238.1 | hypothetical protein | - |
| FGK81_RS08640 (NCTC8193_01721) | - | 1679268..1680092 (-) | 825 | WP_002986242.1 | ATP-binding protein | - |
| FGK81_RS08645 (NCTC8193_01722) | - | 1680093..1680839 (-) | 747 | WP_002986245.1 | conserved phage C-terminal domain-containing protein | - |
| FGK81_RS08650 (NCTC8193_01723) | - | 1680817..1681419 (-) | 603 | WP_002986249.1 | hypothetical protein | - |
| FGK81_RS08655 (NCTC8193_01724) | dnaB | 1681406..1682752 (-) | 1347 | WP_111680752.1 | replicative DNA helicase | - |
| FGK81_RS08660 (NCTC8193_01725) | - | 1682739..1682927 (-) | 189 | WP_002986254.1 | hypothetical protein | - |
| FGK81_RS08665 (NCTC8193_01726) | - | 1682946..1683206 (-) | 261 | WP_002986256.1 | hypothetical protein | - |
| FGK81_RS08670 (NCTC8193_01727) | - | 1683337..1683879 (+) | 543 | WP_002986259.1 | hypothetical protein | - |
| FGK81_RS09890 (NCTC8193_01728) | - | 1683881..1684036 (-) | 156 | WP_002986261.1 | hypothetical protein | - |
| FGK81_RS08675 (NCTC8193_01729) | - | 1684068..1684259 (-) | 192 | WP_002986264.1 | hypothetical protein | - |
| FGK81_RS08680 (NCTC8193_01730) | - | 1684293..1684505 (-) | 213 | WP_002986266.1 | hypothetical protein | - |
| FGK81_RS08685 (NCTC8193_01731) | - | 1684581..1685324 (-) | 744 | WP_002986270.1 | ORF6C domain-containing protein | - |
| FGK81_RS10125 (NCTC8193_01732) | - | 1685321..1685455 (-) | 135 | WP_002986279.1 | hypothetical protein | - |
| FGK81_RS08690 (NCTC8193_01733) | - | 1685529..1685744 (-) | 216 | WP_002986282.1 | hypothetical protein | - |
| FGK81_RS08695 (NCTC8193_01734) | - | 1686055..1686405 (+) | 351 | WP_032467305.1 | helix-turn-helix domain-containing protein | - |
| FGK81_RS08700 (NCTC8193_01735) | - | 1686415..1686795 (+) | 381 | WP_002986288.1 | ImmA/IrrE family metallo-endopeptidase | - |
| FGK81_RS08705 (NCTC8193_01736) | - | 1686807..1687340 (+) | 534 | WP_002986291.1 | hypothetical protein | - |
| FGK81_RS09945 (NCTC8193_01737) | - | 1687467..1688609 (+) | 1143 | WP_181876545.1 | tyrosine-type recombinase/integrase | - |
| FGK81_RS08720 (NCTC8193_01739) | - | 1688985..1690217 (+) | 1233 | WP_011528210.1 | transglutaminase domain-containing protein | - |
| FGK81_RS08725 (NCTC8193_01740) | tadA | 1690831..1691345 (-) | 515 | Protein_1669 | tRNA adenosine(34) deaminase TadA | - |
| FGK81_RS08730 (NCTC8193_01741) | - | 1691345..1692124 (-) | 780 | WP_011888570.1 | MBL fold metallo-hydrolase | - |
| FGK81_RS08735 (NCTC8193_01742) | - | 1692264..1692803 (-) | 540 | WP_011888569.1 | biotin transporter BioY | - |
| FGK81_RS08740 | - | 1692807..1693118 (-) | 312 | Protein_1672 | CHY zinc finger protein | - |
| FGK81_RS08745 (NCTC8193_01743) | tgt | 1693336..1694478 (-) | 1143 | WP_002986319.1 | tRNA guanosine(34) transglycosylase Tgt | - |
| FGK81_RS10155 | - | 1694475..1694660 (-) | 186 | WP_002986321.1 | hypothetical protein | - |
| FGK81_RS08755 (NCTC8193_01744) | - | 1694697..1695560 (+) | 864 | WP_011888568.1 | DUF975 family protein | - |
| FGK81_RS08760 (NCTC8193_01745) | perR | 1695663..1696130 (-) | 468 | WP_002986328.1 | peroxide-responsive transcriptional repressor PerR | - |
| FGK81_RS08765 (NCTC8193_01746) | - | 1696182..1696637 (-) | 456 | WP_011888567.1 | CoA-binding protein | - |
| FGK81_RS08770 (NCTC8193_01747) | polA | 1696815..1699457 (-) | 2643 | WP_011888566.1 | DNA polymerase I | - |
Sequence
Protein
Download Length: 453 a.a. Molecular weight: 49386.68 Da Isoelectric Point: 6.0962
>NTDB_id=1126803 FGK81_RS08375 WP_002986109.1 1634129..1635490(-) (radA) [Streptococcus pyogenes strain NCTC8193]
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRV
LGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNAR
RTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIR
RVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKAVFS
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRV
LGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNAR
RTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIR
RVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKAVFS
Nucleotide
Download Length: 1362 bp
>NTDB_id=1126803 FGK81_RS08375 WP_002986109.1 1634129..1635490(-) (radA) [Streptococcus pyogenes strain NCTC8193]
ATGGCAAAGAAAAAAGCAACCTTTATCTGTCAGGAGTGTGGCTACCAGTCGCCAAAGTATTTAGGGCGCTGTCCAAATTG
CTCGGCCTGGTCTTCTTTTGTGGAAGAAGTAGAGGTCAAAGAAGTCAAAAATGCCCGTGTTAGTCTAGCTGGAGAAAAGT
CCAGACCGGTTAAACTAAAAGATGTGGATAATATTAGTTATCACAGAACACAGACTGACATGTCTGAATTTAATAGAGTT
CTTGGAGGGGGTGTGGTTCCTGGAAGCTTGATTTTAATTGGTGGTGATCCGGGTATTGGAAAATCCACCTTACTCTTGCA
GGTATCCACGCAGCTCGCTAATAAGGGAACGGTTCTCTATGTGTCTGGGGAAGAATCAGCAGAGCAGATTAAACTGCGGA
GTGAGCGTCTGGGTGATATTGACAATGAATTTTACCTCTATGCCGAAACCAATATGCAAGCTATTCGCACAGAAATTGAA
AATATTAAACCAGATTTTTTAATTATTGACTCCATTCAGACCATCATGAGCCCTGATATTACAGGTGTTCAAGGATCAGT
CAGTCAGGTGAGAGAAGTCACTGCAGAATTGATGCAGCTTGCAAAGACGAACAACATTGCAACCTTTATTGTGGGACATG
TTACCAAGGAAGGAACCTTAGCTGGTCCCCGTATGTTAGAACATATGGTGGATACCGTTCTCTACTTTGAAGGGGAAAGG
CATCATACTTTTCGCATCTTGCGGGCGGTGAAAAACCGTTTTGGCTCTACCAACGAGATTGGCATCTTTGAAATGCAGTC
TGGTGGCTTGGTAGAGGTCTTAAATCCTAGTCAAGTCTTTTTAGAGGAACGCTTAGATGGGGCAACAGGATCGGCTGTCG
TTGTAACGATGGAAGGAAGTCGTCCTATTTTAGCAGAGGTGCAATCTTTAGTGACACCAACCGTTTTTGGCAATGCTAGA
CGAACCACTACGGGACTTGATTTCAATCGCGTAAGCCTAATAATGGCAGTTTTAGAAAAGCGCTGTGGTTTACTCTTACA
AAATCAAGATGCCTACCTCAAGTCGGCTGGTGGTGTCAAACTAGACGAACCTGCCATTGATTTGGCAGTCGCTGTGGCTA
TCGCATCCAGTTATAAGGAAAAACCAACCAGCCCTCAAGAAGCTTTCTTAGGCGAGATCGGGTTAACAGGTGAGATTCGG
CGAGTGACCCGTATTGAGCAACGGATTAATGAAGCAGCAAAGCTTGGATTTACCAAGGTCTATGCTCCTAAAAATGCTTT
GCAAGGCATTGATATCCCTCAAGGTATTGAGGTTGTCGGAGTGACTACGGTTGGTCAGGTTTTAAAGGCAGTTTTTAGCT
AG
ATGGCAAAGAAAAAAGCAACCTTTATCTGTCAGGAGTGTGGCTACCAGTCGCCAAAGTATTTAGGGCGCTGTCCAAATTG
CTCGGCCTGGTCTTCTTTTGTGGAAGAAGTAGAGGTCAAAGAAGTCAAAAATGCCCGTGTTAGTCTAGCTGGAGAAAAGT
CCAGACCGGTTAAACTAAAAGATGTGGATAATATTAGTTATCACAGAACACAGACTGACATGTCTGAATTTAATAGAGTT
CTTGGAGGGGGTGTGGTTCCTGGAAGCTTGATTTTAATTGGTGGTGATCCGGGTATTGGAAAATCCACCTTACTCTTGCA
GGTATCCACGCAGCTCGCTAATAAGGGAACGGTTCTCTATGTGTCTGGGGAAGAATCAGCAGAGCAGATTAAACTGCGGA
GTGAGCGTCTGGGTGATATTGACAATGAATTTTACCTCTATGCCGAAACCAATATGCAAGCTATTCGCACAGAAATTGAA
AATATTAAACCAGATTTTTTAATTATTGACTCCATTCAGACCATCATGAGCCCTGATATTACAGGTGTTCAAGGATCAGT
CAGTCAGGTGAGAGAAGTCACTGCAGAATTGATGCAGCTTGCAAAGACGAACAACATTGCAACCTTTATTGTGGGACATG
TTACCAAGGAAGGAACCTTAGCTGGTCCCCGTATGTTAGAACATATGGTGGATACCGTTCTCTACTTTGAAGGGGAAAGG
CATCATACTTTTCGCATCTTGCGGGCGGTGAAAAACCGTTTTGGCTCTACCAACGAGATTGGCATCTTTGAAATGCAGTC
TGGTGGCTTGGTAGAGGTCTTAAATCCTAGTCAAGTCTTTTTAGAGGAACGCTTAGATGGGGCAACAGGATCGGCTGTCG
TTGTAACGATGGAAGGAAGTCGTCCTATTTTAGCAGAGGTGCAATCTTTAGTGACACCAACCGTTTTTGGCAATGCTAGA
CGAACCACTACGGGACTTGATTTCAATCGCGTAAGCCTAATAATGGCAGTTTTAGAAAAGCGCTGTGGTTTACTCTTACA
AAATCAAGATGCCTACCTCAAGTCGGCTGGTGGTGTCAAACTAGACGAACCTGCCATTGATTTGGCAGTCGCTGTGGCTA
TCGCATCCAGTTATAAGGAAAAACCAACCAGCCCTCAAGAAGCTTTCTTAGGCGAGATCGGGTTAACAGGTGAGATTCGG
CGAGTGACCCGTATTGAGCAACGGATTAATGAAGCAGCAAAGCTTGGATTTACCAAGGTCTATGCTCCTAAAAATGCTTT
GCAAGGCATTGATATCCCTCAAGGTATTGAGGTTGTCGGAGTGACTACGGTTGGTCAGGTTTTAAAGGCAGTTTTTAGCT
AG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| radA | Streptococcus mitis NCTC 12261 |
85.872 |
100 |
0.859 |
| radA | Streptococcus pneumoniae D39 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae R6 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae Rx1 |
85.651 |
100 |
0.857 |
| radA | Streptococcus mitis SK321 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae TIGR4 |
85.651 |
100 |
0.857 |
| radA | Bacillus subtilis subsp. subtilis str. 168 |
61.369 |
100 |
0.614 |