Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC   Type   Machinery gene
Locus tag   ELZ66_RS03190 Genome accession   NZ_LR133933
Coordinates   666369..668576 (-) Length   735 a.a.
NCBI ID   WP_011945789.1    Uniprot ID   A0AAN5PJK8
Organism   Legionella pneumophila strain NCTC12180     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 661369..673576
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ66_RS03170 (NCTC12180_00622) - 661845..663773 (-) 1929 WP_011945785.1 hypothetical protein -
  ELZ66_RS03175 (NCTC12180_00623) - 663899..664291 (-) 393 WP_011945786.1 hypothetical protein -
  ELZ66_RS03180 (NCTC12180_00624) - 664428..664805 (+) 378 WP_011945787.1 hypothetical protein -
  ELZ66_RS03185 (NCTC12180_00625) - 665006..666313 (+) 1308 WP_011945788.1 tetratricopeptide repeat protein -
  ELZ66_RS03190 (NCTC12180_00626) comEC 666369..668576 (-) 2208 WP_011945789.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ELZ66_RS03195 (NCTC12180_00627) pilE 668654..669103 (-) 450 WP_010946364.1 type IV pilin protein Machinery gene
  ELZ66_RS03200 (NCTC12180_00628) - 669115..672624 (-) 3510 WP_011945790.1 PilC/PilY family type IV pilus protein -
  ELZ66_RS03205 (NCTC12180_00629) - 672637..673149 (-) 513 WP_011945791.1 pilus assembly protein -

Sequence

Protein


Download         Length: 735 a.a.        Molecular weight: 83328.95 Da        Isoelectric Point: 9.7127

>NTDB_id=1117686 ELZ66_RS03190 WP_011945789.1 666369..668576(-) (comEC) [Legionella pneumophila strain NCTC12180]
MEIYCFLIGVLYAYTYNIYLTIAIPLLFYITPRYPIVLFFIAGCGFALIHQWIVSPKGMPDTQVITQAQLEGTIASIPMQ
RPNKTQFHFAIEKINNNPAQGLIQLNWYNKPPVLRAGQRWQLSVKLKKPRNFRNPGGFNYVRYLAARHIHWTGYIRYGNN
KLISNQPPSFSWLTLREKIGDALTKLAPNTETAGIIEALTLNVTHHISSEHWNLFRRTGTVHLFGISGEHIALVSCIFFI
VIRWIWSMSYRCCLFLPAHTIASIGGLLAALPYAFLAGFEPPVQRALIGCVLYTIYAIGKQRFTPWQIWRYALFLVLCIE
PHAVFLQGFYFSFLAVACLLLTHQRWPLKNYKKTLTLQLSCLIGLMPLTLHWYSYGSINGFLANLFSIPLVSFLIVPLAL
MTMITSPLHWSWILMKPLAWLVALLLQGLTYVEQIAGINITWSITSVTMMLAMTAGLFLRVLLPVKPFKHLAILWIILPL
FPPRTAIYPGEALINILDVGQGLAVAIQTQHHVLLYDTGDSYFQGSDLGQMAIIPFFRSIGIKTIDKIVISHPDKDHKGG
LNSLEKEMQVNQLIVNDPYFYKRGSNCHSYPQWQWDGVSFRFLPIKESFTKKNNNSCILQVSNSAGRVLLTGDIEKAAEE
YLVRNYGSQLASEILVVPHHGSKTSSSYRFLLEVNPLYAIASLGFDNRFKFPHSKTLQSMKTLDITFFRTDECGMAAIKL
PASGQVHRPSCMQAN

Nucleotide


Download         Length: 2208 bp        

>NTDB_id=1117686 ELZ66_RS03190 WP_011945789.1 666369..668576(-) (comEC) [Legionella pneumophila strain NCTC12180]
ATGGAAATTTATTGCTTTTTAATAGGCGTACTTTATGCCTATACCTATAATATTTATCTAACTATTGCGATTCCTTTACT
CTTTTATATCACACCAAGATATCCAATTGTCCTGTTCTTCATCGCCGGGTGCGGCTTTGCCCTGATTCATCAGTGGATTG
TATCTCCCAAGGGCATGCCTGATACGCAAGTAATCACTCAAGCCCAATTGGAAGGAACAATTGCTTCCATCCCCATGCAA
CGTCCTAACAAAACTCAATTCCATTTTGCAATTGAAAAAATTAATAATAACCCTGCTCAAGGCTTGATCCAATTAAACTG
GTATAACAAACCTCCTGTCTTACGAGCCGGTCAGCGATGGCAACTTTCAGTGAAACTAAAAAAACCTCGTAATTTCCGCA
ACCCAGGAGGTTTTAATTATGTACGTTACCTGGCGGCTCGTCATATCCATTGGACTGGTTATATTCGTTATGGGAATAAT
AAGCTAATTAGCAATCAACCCCCTTCTTTCAGTTGGTTAACACTGCGTGAAAAAATAGGGGATGCTTTGACAAAACTGGC
ACCGAATACAGAAACGGCAGGCATCATCGAAGCATTGACGTTAAATGTTACTCACCATATCAGTTCAGAACATTGGAATT
TGTTCCGAAGAACAGGAACGGTACATTTATTCGGGATTTCAGGGGAGCACATCGCTCTGGTCTCCTGCATTTTCTTTATA
GTGATAAGATGGATTTGGTCAATGAGCTATCGTTGCTGTTTGTTCTTACCGGCCCATACCATAGCGAGTATCGGTGGGCT
ACTGGCCGCCTTGCCCTATGCTTTTTTAGCCGGGTTTGAACCTCCTGTACAGCGTGCTTTAATTGGTTGTGTACTTTACA
CAATATACGCCATAGGAAAACAACGTTTTACACCATGGCAAATATGGAGATACGCCTTATTTTTAGTCTTGTGTATTGAA
CCCCATGCCGTATTCCTGCAAGGTTTTTATTTTTCATTTCTTGCTGTGGCCTGTCTTCTATTGACGCACCAACGTTGGCC
ACTGAAAAATTATAAAAAAACACTGACATTACAATTAAGCTGCCTCATTGGATTGATGCCCTTGACTCTCCATTGGTACT
CCTATGGTTCTATTAATGGATTCCTTGCCAATTTATTCTCCATACCTTTAGTCAGCTTTCTGATAGTACCCTTGGCTTTA
ATGACTATGATAACGAGTCCGCTTCATTGGTCCTGGATATTGATGAAACCATTGGCATGGCTTGTTGCCCTGTTACTGCA
AGGACTAACGTATGTTGAGCAAATAGCAGGGATTAATATCACCTGGTCCATCACCTCGGTAACAATGATGCTCGCTATGA
CAGCAGGTCTGTTTTTAAGGGTATTATTACCTGTCAAGCCATTCAAACACTTGGCTATCCTTTGGATTATCCTTCCCTTA
TTTCCGCCTCGTACTGCAATTTATCCAGGGGAAGCATTAATTAATATTTTGGATGTTGGGCAAGGACTGGCTGTTGCGAT
ACAAACGCAACATCATGTTTTACTCTACGATACGGGAGATTCCTATTTTCAGGGGAGTGATTTAGGGCAAATGGCGATAA
TACCCTTTTTCAGGTCAATTGGAATAAAAACAATTGACAAAATAGTAATAAGCCATCCTGATAAAGATCATAAGGGCGGA
TTAAATTCCCTTGAAAAAGAGATGCAAGTCAATCAATTAATAGTGAATGATCCCTATTTTTATAAACGTGGAAGTAATTG
TCATTCATACCCACAATGGCAATGGGATGGGGTGAGTTTTCGTTTTTTACCCATCAAGGAATCTTTCACTAAAAAAAATA
ACAATTCTTGTATCTTACAGGTAAGTAATTCAGCTGGCAGGGTTTTATTAACGGGAGATATTGAAAAAGCGGCTGAAGAG
TACCTGGTAAGAAACTACGGCAGTCAGCTGGCATCCGAGATTTTAGTTGTGCCTCATCATGGGAGTAAAACGTCTTCATC
CTATCGATTTTTGCTGGAAGTAAACCCGCTTTATGCCATTGCATCCTTAGGATTTGATAATCGTTTCAAATTTCCACATT
CTAAAACTTTGCAAAGCATGAAAACATTAGATATCACTTTTTTTAGAACAGACGAATGCGGAATGGCAGCAATCAAACTA
CCTGCATCAGGTCAAGTTCACAGACCAAGTTGTATGCAGGCTAATTGA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(199-464)

Metallo-beta-lactamase superfamily (Lactamase_B)

(498-579)

Domain of unknown function (DUF4131) (DUF4131)

(21-158)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC Legionella pneumophila strain ERS1305867

99.456

100

0.995
  comEC Legionella pneumophila strain Lp02

96.594

99.864

0.965

Multiple sequence alignment