Detailed information NTG1111765

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: HMPREF9425_RS07740
• Genome accession: NZ_GL831112
• Coordinates: 1602330..1603229 (-)
• Length: 299 a.a.
• NCBI ID: WP_003098001.1
• Uniprot ID: -
• Organism: Streptococcus vestibularis ATCC 49124
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1597330..1608229

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF9425_RS10410 (HMPREF9425_1615)	-	1598707..1599051 (+)	345	WP_227278548.1	urease cluster protein	-
HMPREF9425_RS10415 (HMPREF9425_1616)	-	1599100..1599573 (+)	474	WP_244265345.1	DUF4153 domain-containing protein	-
HMPREF9425_RS07730 (HMPREF9425_1617)	-	1599625..1599957 (-)	333	WP_003097990.1	DUF805 domain-containing protein	-
HMPREF9425_RS07735	-	1600068..1602163 (-)	2096	Protein_1574	peptide cleavage/export ABC transporter	-
-	comS	1602179..1602241 (-)	63	-	-	Regulator
HMPREF9425_RS07740 (HMPREF9425_1620)	comR	1602330..1603229 (-)	900	WP_003098001.1	helix-turn-helix transcriptional regulator	Regulator
HMPREF9425_RS07745 (HMPREF9425_1621)	-	1603385..1604035 (-)	651	WP_003092134.1	phosphatase PAP2 family protein	-
HMPREF9425_RS07750 (HMPREF9425_1622)	-	1604038..1604595 (-)	558	WP_037621581.1	ECF transporter S component	-
HMPREF9425_RS07755 (HMPREF9425_1623)	-	1604905..1605414 (-)	510	WP_003092259.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
HMPREF9425_RS07760 (HMPREF9425_1624)	trkA	1605702..1607051 (+)	1350	WP_003098008.1	Trk system potassium transporter TrkA	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35115.51 Da
• Isoelectric Point: 5.1055

>NTDB_id=1111765 HMPREF9425_RS07740 WP_003098001.1 1602330..1603229(-) (comR) [Streptococcus vestibularis ATCC 49124]
MSIKDSIGLRIKTERECQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDKLSYIAKRLGKSMADLLDHDRIEIPDTYYE
MKNRLIKFPTYGDKERVKQKLDLIEDVYDQFFDILPEEELLTLDILENILSFISWEERPKVEEIYEDLFEQVKRKKKFST
NDLLVIYYYFYHLYGRKQYDKKIFDRIVDRVLKQNIPTDDAYNIALFNDLMAIAGLKISLESFKDFLTVIDKLLAVIEKS
QFHSYKPGVYILEAKYELIHNGNKKKAAENYDKAIMFASVLEDSVLEEKTRAEKAADGL

Nucleotide

• Length: 900 bp

>NTDB_id=1111765 HMPREF9425_RS07740 WP_003098001.1 1602330..1603229(-) (comR) [Streptococcus vestibularis ATCC 49124]
TTGAGCATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAATGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAAGGAGAGTCTCTCCCTTCTTTGGATAAATTATCCT
ACATAGCAAAACGTCTGGGAAAAAGCATGGCTGACTTATTGGACCATGACAGGATTGAAATTCCTGACACTTACTATGAG
ATGAAAAATCGTTTAATAAAGTTCCCAACGTACGGAGATAAGGAGAGAGTTAAACAGAAGTTGGATCTTATTGAAGATGT
GTATGATCAATTCTTTGATATTCTTCCAGAAGAGGAACTATTGACTCTAGATATTCTCGAAAATATATTGAGTTTTATCA
GTTGGGAGGAGAGACCTAAAGTCGAAGAAATCTATGAAGATTTGTTTGAACAGGTCAAAAGAAAGAAGAAGTTTTCAACT
AATGATTTGTTAGTTATTTATTATTATTTCTATCATCTTTATGGGAGAAAGCAGTATGATAAAAAGATTTTTGACAGAAT
AGTAGATAGAGTATTAAAGCAAAACATCCCAACAGATGATGCTTATAATATTGCCTTATTTAATGATTTGATGGCTATAG
CTGGGTTAAAGATTTCTCTTGAGTCCTTTAAAGATTTCTTAACAGTAATAGATAAACTATTAGCTGTCATAGAAAAATCA
CAGTTTCATAGTTATAAACCAGGTGTCTATATTTTAGAAGCTAAGTATGAGCTTATACATAATGGGAACAAGAAAAAAGC
TGCTGAAAACTATGATAAAGCTATAATGTTTGCGTCGGTTTTAGAAGATTCCGTTTTGGAAGAAAAGACTCGAGCAGAGA
AAGCGGCAGATGGTTTGTAA

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (75-293)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus salivarius SK126	83.946	100	0.839
comR	Streptococcus salivarius strain HSISS4	82.943	100	0.829
comR	Streptococcus thermophilus LMG 18311	81.605	100	0.816
comR	Streptococcus thermophilus LMD-9	80.936	100	0.809
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	43.478	100	0.435
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	43.144	100	0.431