Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE2   Type   Regulator
Locus tag   ACNR93_RS08260 Genome accession   NZ_CP184736
Coordinates   1674329..1675057 (-) Length   242 a.a.
NCBI ID   WP_420543554.1    Uniprot ID   -
Organism   Streptococcus equinus strain NM-2-29     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1669329..1680057
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACNR93_RS08230 (ACNR93_08230) - 1669664..1670605 (-) 942 WP_074480707.1 3'-5' exoribonuclease YhaM family protein -
  ACNR93_RS08235 (ACNR93_08235) rmuC 1670595..1671809 (-) 1215 WP_398575867.1 DNA recombination protein RmuC -
  ACNR93_RS08240 (ACNR93_08240) - 1671872..1672504 (-) 633 WP_420543552.1 thiamine diphosphokinase -
  ACNR93_RS08245 (ACNR93_08245) rpe 1672497..1673159 (-) 663 WP_420543553.1 ribulose-phosphate 3-epimerase -
  ACNR93_RS08250 (ACNR93_08250) rsgA 1673166..1674038 (-) 873 WP_303189848.1 ribosome small subunit-dependent GTPase A -
  ACNR93_RS08260 (ACNR93_08260) comE/comE2 1674329..1675057 (-) 729 WP_420543554.1 LytR/AlgR family response regulator transcription factor Regulator
  ACNR93_RS08265 (ACNR93_08265) comD/comD3 1675675..1677066 (-) 1392 WP_420543555.1 sensor histidine kinase Regulator
  ACNR93_RS08270 (ACNR93_08270) comD/comD3 1677063..1678145 (-) 1083 WP_420543556.1 sensor histidine kinase Regulator
  ACNR93_RS08275 (ACNR93_08275) comD/comD3 1678438..1679832 (-) 1395 WP_420543557.1 sensor histidine kinase Regulator
  ACNR93_RS08280 (ACNR93_08280) - 1679833..1680030 (-) 198 WP_126438119.1 hypothetical protein -

Sequence

Protein


Download         Length: 242 a.a.        Molecular weight: 28354.62 Da        Isoelectric Point: 6.4937

>NTDB_id=1110965 ACNR93_RS08260 WP_420543554.1 1674329..1675057(-) (comE/comE2) [Streptococcus equinus strain NM-2-29]
MIDIYVLEDNVNQQFRIERMIDELLDENQWDYRHFEIFSEPSHFPNFVEESCPQIFFLDIDINGDNKKGIEVAKKIREKS
RTATIVFVTTHSEFMLLTYRAQVSALDFIDKADEDNSIKINLKNCLRKVIENQALTMPQEFFVFENNKATIRIPMDEILY
FETAESHRLKLVTKSGQRNFYGSIKEVMAANQTFFRSHKSYLINLDNVVCLDKKNSLVHFVGGQSCLVSKKYIKELKLKL
CV

Nucleotide


Download         Length: 729 bp        

>NTDB_id=1110965 ACNR93_RS08260 WP_420543554.1 1674329..1675057(-) (comE/comE2) [Streptococcus equinus strain NM-2-29]
ATGATTGACATCTATGTATTGGAGGACAATGTAAATCAGCAATTTCGGATTGAAAGGATGATTGATGAACTACTTGATGA
AAATCAGTGGGACTATCGTCATTTTGAAATATTTAGTGAGCCGTCTCATTTTCCAAATTTTGTTGAGGAATCTTGCCCAC
AAATTTTTTTCTTAGATATTGATATCAATGGTGATAATAAAAAGGGAATTGAAGTCGCTAAGAAAATTAGGGAGAAATCT
AGAACAGCTACGATTGTTTTTGTTACGACGCATTCCGAGTTTATGTTGTTGACTTACCGAGCACAGGTTAGTGCACTTGA
TTTTATTGATAAAGCAGATGAAGACAATTCGATAAAAATTAATTTAAAAAATTGTTTGCGAAAGGTCATCGAAAATCAGG
CTCTTACGATGCCACAGGAATTTTTTGTATTTGAAAATAATAAAGCTACTATTCGTATTCCGATGGATGAAATTCTTTAT
TTTGAAACAGCTGAAAGTCATCGACTGAAGTTGGTTACAAAGTCAGGACAACGTAATTTTTATGGTTCAATCAAAGAAGT
AATGGCTGCTAATCAGACCTTTTTTAGAAGCCACAAATCGTATCTGATTAATCTTGATAATGTTGTGTGCTTAGATAAAA
AGAATAGTTTGGTGCATTTTGTCGGTGGTCAATCTTGCCTTGTTTCAAAGAAATACATTAAAGAATTAAAGTTGAAATTA
TGTGTTTAG

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(149-239)

Response regulator receiver domain (Response_reg)

(6-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE2 Streptococcus equinus JB1

74.167

99.174

0.736
  comE/comE1 Streptococcus equinus JB1

44.118

98.347

0.434
  comE/blpR Streptococcus mutans UA159

40

99.174

0.397
  comE/comE2 Streptococcus gordonii strain NCTC7865

38.776

100

0.393
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

38.776

100

0.393

Multiple sequence alignment