Detailed information NTG1109471

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACOCJB_RS11110
• Genome accession: NZ_CP184557
• Coordinates: 2240563..2241450 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain SCTW2018482
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2235563..2246450

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACOCJB_RS11080 (ACOCJB_11080)	-	2236296..2237057 (+)	762	WP_000323448.1	alpha/beta hydrolase	-
ACOCJB_RS11085 (ACOCJB_11085)	-	2237301..2237756 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACOCJB_RS11090 (ACOCJB_11090)	-	2237878..2237979 (+)	102	WP_000731972.1	SE2200 family small protein	-
ACOCJB_RS11095 (ACOCJB_11095)	-	2238039..2239463 (-)	1425	WP_000953736.1	alkaline phosphatase	-
ACOCJB_RS11100 (ACOCJB_11100)	-	2239661..2239861 (+)	201	WP_000604731.1	hypothetical protein	-
ACOCJB_RS11105 (ACOCJB_11105)	braR	2239887..2240552 (+)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACOCJB_RS11110 (ACOCJB_11110)	braS	2240563..2241450 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACOCJB_RS11115 (ACOCJB_11115)	-	2241558..2242313 (+)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
ACOCJB_RS11120 (ACOCJB_11120)	-	2242310..2244310 (+)	2001	WP_000776741.1	ABC transporter permease	-
ACOCJB_RS11125 (ACOCJB_11125)	-	2244979..2245092 (+)	114	WP_014937089.1	hypothetical protein	-
ACOCJB_RS11130 (ACOCJB_11130)	-	2245474..2245734 (+)	261	WP_014937088.1	hypothetical protein	-
ACOCJB_RS11135 (ACOCJB_11135)	-	2245744..2246241 (+)	498	WP_001065267.1	glutathione peroxidase	-
ACOCJB_RS11140 (ACOCJB_11140)	-	2246349..2246441 (-)	93	WP_031774855.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=1109471 ACOCJB_RS11110 WP_000143420.1 2240563..2241450(+) (braS) [Staphylococcus aureus strain SCTW2018482]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1109471 ACOCJB_RS11110 WP_000143420.1 2240563..2241450(+) (braS) [Staphylococcus aureus strain SCTW2018482]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993