Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   ACM6AH_RS08110 Genome accession   NZ_CP181115
Coordinates   1655624..1656598 (-) Length   324 a.a.
NCBI ID   WP_000697220.1    Uniprot ID   W8U5L8
Organism   Staphylococcus aureus strain AG21-0608     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1650624..1661598
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACM6AH_RS08070 (ACM6AH_08070) gcvT 1651125..1652216 (-) 1092 WP_000093349.1 glycine cleavage system aminomethyltransferase GcvT -
  ACM6AH_RS08075 (ACM6AH_08075) - 1652375..1652899 (-) 525 WP_001015120.1 shikimate kinase -
  ACM6AH_RS08080 (ACM6AH_08080) - 1652889..1653035 (-) 147 WP_001792109.1 hypothetical protein -
  ACM6AH_RS08085 (ACM6AH_08085) comGF 1653132..1653629 (-) 498 WP_001788897.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACM6AH_RS08090 (ACM6AH_08090) comGE 1653547..1653846 (-) 300 WP_000844410.1 hypothetical protein Machinery gene
  ACM6AH_RS08095 (ACM6AH_08095) comGD 1653833..1654279 (-) 447 WP_416152757.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACM6AH_RS08100 (ACM6AH_08100) comGC 1654257..1654568 (-) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  ACM6AH_RS08105 (ACM6AH_08105) comGB 1654582..1655652 (-) 1071 WP_000776422.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACM6AH_RS08110 (ACM6AH_08110) comGA 1655624..1656598 (-) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  ACM6AH_RS08115 (ACM6AH_08115) - 1656650..1657273 (-) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  ACM6AH_RS08120 (ACM6AH_08120) - 1657270..1657599 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  ACM6AH_RS08125 (ACM6AH_08125) - 1657599..1658585 (-) 987 WP_000161311.1 ROK family glucokinase -
  ACM6AH_RS08130 (ACM6AH_08130) - 1658582..1658785 (-) 204 WP_000087561.1 YqgQ family protein -
  ACM6AH_RS08135 (ACM6AH_08135) - 1658766..1660229 (-) 1464 WP_001017852.1 rhomboid family protein -
  ACM6AH_RS08140 (ACM6AH_08140) - 1660241..1660780 (-) 540 WP_000164546.1 5-formyltetrahydrofolate cyclo-ligase -
  ACM6AH_RS08145 (ACM6AH_08145) rpmG 1660989..1661138 (-) 150 WP_001265709.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36897.96 Da        Isoelectric Point: 8.8516

>NTDB_id=1098527 ACM6AH_RS08110 WP_000697220.1 1655624..1656598(-) (comGA) [Staphylococcus aureus strain AG21-0608]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=1098527 ACM6AH_RS08110 WP_000697220.1 1655624..1656598(-) (comGA) [Staphylococcus aureus strain AG21-0608]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGGCCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATCGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGCGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W8U5L8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

100

100

1
  comGA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment