Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   ACDW38_RS23575 Genome accession   NZ_CP167986
Coordinates   5089962..5091299 (+) Length   445 a.a.
NCBI ID   WP_003110427.1    Uniprot ID   -
Organism   Pseudomonas aeruginosa strain 0805d0     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 5084962..5096299
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACDW38_RS23550 (ACDW38_23550) pgeF 5085105..5085833 (-) 729 WP_012614543.1 peptidoglycan editing factor PgeF -
  ACDW38_RS23555 (ACDW38_23555) rluD 5085830..5086792 (-) 963 WP_003094686.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD -
  ACDW38_RS23560 (ACDW38_23560) - 5086938..5087963 (+) 1026 WP_003102590.1 outer membrane protein assembly factor BamD -
  ACDW38_RS23565 (ACDW38_23565) - 5088120..5088365 (+) 246 WP_023115580.1 PP0621 family protein -
  ACDW38_RS23570 (ACDW38_23570) pilS 5088355..5089947 (+) 1593 WP_003094692.1 two-component system sensor histidine kinase PilS Regulator
  ACDW38_RS23575 (ACDW38_23575) pilR 5089962..5091299 (+) 1338 WP_003110427.1 two-component system response regulator PilR Regulator
  ACDW38_RS23580 (ACDW38_23580) thiO 5091345..5092439 (-) 1095 WP_023103512.1 glycine oxidase ThiO -
  ACDW38_RS23585 (ACDW38_23585) - 5092579..5093079 (+) 501 WP_003116259.1 GspH/FimT family pseudopilin -
  ACDW38_RS23590 (ACDW38_23590) - 5093202..5093690 (+) 489 WP_003141552.1 GspH/FimT family pseudopilin -
  ACDW38_RS23595 (ACDW38_23595) pilV 5093700..5094224 (+) 525 WP_003116261.1 type IV pilus modification protein PilV Machinery gene
  ACDW38_RS23600 (ACDW38_23600) - 5094233..5095048 (+) 816 WP_003116262.1 PilW family protein -
  ACDW38_RS23605 (ACDW38_23605) - 5095045..5095650 (+) 606 WP_003116263.1 PilX N-terminal domain-containing pilus assembly protein -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49723.03 Da        Isoelectric Point: 5.8638

>NTDB_id=1040863 ACDW38_RS23575 WP_003110427.1 5089962..5091299(+) (pilR) [Pseudomonas aeruginosa strain 0805d0]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLADRI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=1040863 ACDW38_RS23575 WP_003110427.1 5089962..5091299(+) (pilR) [Pseudomonas aeruginosa strain 0805d0]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGATCGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTATACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCGGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGATATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

Sigma-54 interaction domain (Sigma54_activat)

(135-301)

Response regulator receiver domain (Response_reg)

(7-115)

Bacterial regulatory protein, Fis family (HTH_8)

(402-442)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

99.775

100

0.998
  pilR Acinetobacter baumannii strain A118

51.198

100

0.528
  luxO Vibrio cholerae strain A1552

38.17

100

0.384

Multiple sequence alignment