Detailed information NTG1020685

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: AB1F71_RS07030
• Genome accession: NZ_CP160386
• Coordinates: 1450420..1451301 (-)
• Length: 293 a.a.
• NCBI ID: WP_002262935.1
• Uniprot ID: Q8DT59
• Organism: Streptococcus mutans strain UA159 ykuR deletion
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1445420..1456301

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB1F71_RS07005 (AB1F71_07005)	vicR	1446314..1447021 (-)	708	WP_002262930.1	response regulator YycF	Regulator
AB1F71_RS07010 (AB1F71_07010)	-	1447374..1448156 (+)	783	WP_002262931.1	amino acid ABC transporter ATP-binding protein	-
AB1F71_RS07015 (AB1F71_07015)	-	1448153..1448965 (+)	813	WP_002262932.1	transporter substrate-binding domain-containing protein	-
AB1F71_RS07020 (AB1F71_07020)	-	1448983..1449687 (+)	705	WP_002262933.1	amino acid ABC transporter permease	-
AB1F71_RS07025 (AB1F71_07025)	-	1449702..1450352 (+)	651	WP_002262934.1	amino acid ABC transporter permease	-
AB1F71_RS07030 (AB1F71_07030)	endA	1450420..1451301 (-)	882	WP_002262935.1	DNA/RNA non-specific endonuclease	Machinery gene
AB1F71_RS07035 (AB1F71_07035)	-	1451343..1451531 (-)	189	WP_002262936.1	DNA-directed RNA polymerase subunit beta	-
AB1F71_RS07040 (AB1F71_07040)	murA	1451534..1452805 (-)	1272	WP_002262937.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
AB1F71_RS07045 (AB1F71_07045)	-	1452871..1453104 (-)	234	WP_002285829.1	DUF1146 family protein	-
AB1F71_RS07050 (AB1F71_07050)	-	1453377..1453793 (-)	417	WP_002262939.1	F0F1 ATP synthase subunit epsilon	-
AB1F71_RS07055 (AB1F71_07055)	atpD	1453807..1455213 (-)	1407	WP_002262940.1	F0F1 ATP synthase subunit beta	-
AB1F71_RS07060 (AB1F71_07060)	-	1455239..1456117 (-)	879	WP_002262941.1	F0F1 ATP synthase subunit gamma	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 32130.72 Da
• Isoelectric Point: 9.5337

>NTDB_id=1020685 AB1F71_RS07030 WP_002262935.1 1450420..1451301(-) (endA) [Streptococcus mutans strain UA159 ykuR deletion]
MTRKTNKSQRKQQKLCLSLLAALSVFVCTYIATSDHIADSNPIKQAAQLLTGKNKDILSNGSMSHQATPSQELANTVMTD
AVKNALGRQIEWSGAGSFIINHNKTDLNADVASQPYASNQTKIVQGQTVPTVANALLSKATRQYRNRQETGNGRTNWQPA
GWHQLYDLPGDYDHAVDRGHLLAYALVGGLKRFDASTSNPQNVATQAAWANEANSSNSRGQNYYETLIRKALDSHKRVRY
RVTLIYDDNNDILASGSHLEAKSSDGSLEFNVFIPNVQSGLTFDYATGQVKAN

Nucleotide

• Length: 882 bp

>NTDB_id=1020685 AB1F71_RS07030 WP_002262935.1 1450420..1451301(-) (endA) [Streptococcus mutans strain UA159 ykuR deletion]
ATGACTAGAAAAACGAACAAGTCTCAGCGAAAACAGCAAAAATTATGCTTATCTCTCCTTGCTGCTTTGAGCGTATTTGT
TTGTACTTATATTGCAACCAGTGATCATATTGCTGATAGTAACCCTATAAAGCAGGCTGCCCAATTATTGACAGGTAAAA
ACAAGGATATACTTTCAAATGGTTCAATGAGCCATCAAGCGACTCCCAGTCAAGAATTAGCCAATACTGTTATGACGGAT
GCAGTAAAAAATGCCTTGGGTAGACAAATTGAATGGAGTGGTGCAGGTTCTTTCATTATTAATCATAATAAAACTGACCT
TAACGCTGATGTTGCTAGCCAACCGTATGCTAGTAATCAGACCAAAATCGTTCAAGGACAGACAGTACCAACAGTAGCAA
ATGCTTTGTTAAGTAAGGCTACTCGTCAGTACCGAAACCGCCAAGAGACAGGAAATGGCAGGACAAATTGGCAGCCAGCA
GGCTGGCATCAGCTTTATGATTTGCCGGGTGACTATGATCACGCGGTTGATCGTGGACACTTATTGGCTTATGCTTTGGT
TGGTGGTTTGAAACGATTTGATGCTTCAACGAGTAATCCTCAAAATGTAGCAACACAAGCAGCTTGGGCTAATGAAGCCA
ATAGTTCAAACTCAAGGGGACAAAATTATTATGAAACACTGATTAGAAAAGCTTTGGATAGTCATAAGCGTGTTCGTTAT
CGTGTGACTCTTATCTATGATGACAACAATGATATCTTAGCCAGTGGCAGTCATCTAGAAGCCAAATCATCAGATGGCAG
TCTAGAGTTCAATGTCTTTATTCCTAATGTTCAAAGCGGTTTGACCTTTGATTATGCAACAGGACAAGTTAAGGCAAATT
AA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (99-251)

3D structure

• AlphaFold DB: Q8DT59

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	64.103	79.863	0.512
endA	Streptococcus pneumoniae D39	64.103	79.863	0.512
endA	Streptococcus pneumoniae R6	64.103	79.863	0.512
endA	Streptococcus pneumoniae TIGR4	64.103	79.863	0.512