Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   DQL30_RS02790 Genome accession   NZ_LS483333
Coordinates   523227..523868 (+) Length   213 a.a.
NCBI ID   WP_002991888.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC12048     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 518227..528868
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL30_RS02770 (NCTC12048_00547) - 518784..519524 (+) 741 WP_002983660.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  DQL30_RS02775 (NCTC12048_00548) pknB 519521..521419 (+) 1899 WP_111713663.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  DQL30_RS02780 (NCTC12048_00549) liaF 521541..522233 (+) 693 WP_011054833.1 cell wall-active antibiotics response protein LiaF -
  DQL30_RS02785 (NCTC12048_00550) - 522230..523234 (+) 1005 WP_002991890.1 sensor histidine kinase -
  DQL30_RS02790 (NCTC12048_00551) vraR 523227..523868 (+) 642 WP_002991888.1 response regulator transcription factor Regulator
  DQL30_RS02795 (NCTC12048_00552) - 523905..525305 (+) 1401 WP_023079249.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DQL30_RS02800 (NCTC12048_00553) - 525305..525682 (+) 378 WP_023610575.1 S1 RNA-binding domain-containing protein -
  DQL30_RS02805 (NCTC12048_00554) cysK 525700..526641 (-) 942 WP_011888673.1 cysteine synthase A -
  DQL30_RS02810 (NCTC12048_00555) - 526769..527401 (-) 633 WP_009880468.1 YigZ family protein -
  DQL30_RS02815 (NCTC12048_00556) comFA/cflA 527457..528782 (+) 1326 WP_111713664.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23767.50 Da        Isoelectric Point: 5.1640

>NTDB_id=1017972 DQL30_RS02790 WP_002991888.1 523227..523868(+) (vraR) [Streptococcus pyogenes strain NCTC12048]
MSKIKVILVDDHEMVRMGLKSFLNLQADIDVVGEASNGREGVDLALALKPDVLVMDLVMPELGGVEATLEVLKKWKEAKV
LVLTSYLDNEKIYPVIDAGAKGYMLKTCSAAEILNAIRKVSKGELAIETEVDKKIKAHDQHPDLHEELTAREYDILHLLA
KGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFRHHLVPQDDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=1017972 DQL30_RS02790 WP_002991888.1 523227..523868(+) (vraR) [Streptococcus pyogenes strain NCTC12048]
ATGAGTAAGATAAAAGTGATATTGGTCGATGATCATGAAATGGTCCGCATGGGACTTAAGAGTTTTTTGAATTTACAAGC
TGATATTGATGTCGTTGGTGAAGCCTCTAATGGACGTGAAGGGGTTGATTTGGCATTGGCCTTGAAGCCAGATGTTTTGG
TTATGGATCTAGTGATGCCAGAGTTAGGCGGTGTTGAGGCAACTTTAGAAGTCCTAAAAAAATGGAAAGAGGCTAAGGTA
CTTGTGTTAACTTCCTATCTAGATAATGAAAAGATATACCCTGTCATTGATGCTGGTGCTAAAGGTTACATGTTAAAGAC
TTGTAGTGCAGCCGAAATTCTAAATGCTATTCGGAAAGTTTCAAAAGGTGAATTGGCCATTGAAACAGAAGTTGACAAAA
AAATTAAGGCGCATGATCAACACCCTGACTTGCATGAGGAACTAACAGCGCGTGAGTATGATATTTTACACCTTTTAGCT
AAAGGGTATGATAATCAGACCATCGCTGATGAACTCTTTATTTCCTTAAAAACCGTCAAAACACATGTGTCCAATATTCT
AGCCAAGTTAGAAGTTGATGACCGAACCCAAGCGGTTGTCTATGCTTTTCGACACCATTTAGTCCCCCAAGACGATAATT
AA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.913

96.714

0.512
  degU Bacillus subtilis subsp. subtilis str. 168

36.283

100

0.385

Multiple sequence alignment