Detailed information    

insolico Bioinformatically predicted

Overview

Name   rexA   Type   Machinery gene
Locus tag   H1W81_RS02775 Genome accession   NZ_LR824002
Coordinates   513742..517395 (+) Length   1217 a.a.
NCBI ID   WP_179971682.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_67     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 508742..522395
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W81_RS09845 - 508808..509238 (+) 431 Protein_488 LytTR family DNA-binding domain-containing protein -
  H1W81_RS09850 (STHERMO_0586) - 509291..509942 (+) 652 Protein_489 hypothetical protein -
  H1W81_RS02770 (STHERMO_0588) rexB 510432..513752 (+) 3321 WP_011226521.1 ATP-dependent nuclease subunit B Machinery gene
  H1W81_RS02775 (STHERMO_0589) rexA 513742..517395 (+) 3654 WP_179971682.1 helicase-exonuclease AddAB subunit AddA Machinery gene
  H1W81_RS02780 (STHERMO_0590) - 517789..518522 (-) 734 Protein_492 DUF554 domain-containing protein -
  H1W81_RS02785 (STHERMO_0593) - 518796..519528 (+) 733 Protein_493 ABC transporter ATP-binding protein -
  H1W81_RS02790 (STHERMO_0594) - 519531..521120 (+) 1590 WP_011226516.1 hypothetical protein -
  H1W81_RS02795 (STHERMO_0595) proB 521241..522044 (+) 804 WP_002948808.1 glutamate 5-kinase -

Sequence

Protein


Download         Length: 1217 a.a.        Molecular weight: 138426.53 Da        Isoelectric Point: 4.7169

>NTDB_id=1012138 H1W81_RS02775 WP_179971682.1 513742..517395(+) (rexA) [Streptococcus thermophilus isolate STH_CIRM_67]
MLTKAFLSPAEIEERIAQEAASDKDRKLTPEQIEAIYSNGTNILVSASAGSGKTFVMVERILDMIGRGVGIDQLFISTFT
VKAAGELKERLEKRLTKHLGQAETDEERAFLSDQIAKIGTADIGTMDAFTQKLVNQYGYLLGVSPTFRIMTDLAEQTLMK
NEVYADLFNDYMQGKDAQLFQKLVRNFTGHSKTSKAFRDLVYDIYSFSQATADPEKWLCQNLLKGQIEAKPEQAKNELLD
GLKDGLLADFLAFLRDHLGIAQREFAKAKYLNNVSDAIILLEGSLINDQTDMEDLLKQLLTLSGGTGLTNMTRPKDEELK
AYKEAYNKTKNEFVAQLREVDTQLTVLEVLTKHNDDILPMLELLQSFVLDFSDQYLQAKIQENTFEFSDIAHFAIRILEE
NPEVAVSYRDRYHEVMVDEYQDNSHTQERMLELLSNGHNRFMVGDIKQSIYRFRQADPQIFNDKFQLFLENPDAGKLILL
KENFRSQSEVLDATNGVFSHLMDQEIGDILYDKTHMLVAGSQKQKEPHPENETEVLIYNSDESSTSEDEEGPDQAISSGE
ISLVIKEIIKLHEQGVRFEDITLLAPNRNTYLDLMVSFEEHGIPLVPDEYKSSYLESLEVMIMLDTLRAINNPLNDYALV
ALLRSPMFNFNEDDLTRIAVQADKGQFYDKLLAAHTKSGLHPEVVMQGLEAKLTLFTETLADWRDYSKCHSIYDLIWKIY
NDRFYYDYVGGLPRAEQRQANLYALALRANAYEKTGFKGLSRFIGMIDKIIASGNDLEEVTDLVPKNAVSLMTIHKSKGL
EFKYVFVLQMNRKFIGHSKDGLSGKYIINREKGLGIKYLADLKDQINTNLPKLNVVLETLTFQENRREERRASISEEMRL
LYVAMTRAEKKLYLVGKGSKETLTQQYGTDVENNRLPVALRDQIATYQDWIMALDTAFMRKDLKFTVRFVEDEELTPEAI
GQVEVKAAVDADDLSNNRQTEEIERALTVLESVEKLNHLYAPAIDLPSVRTPSQLKTFYEPIMDTEGVDIMDKKEVVQPL
ETASTFELPDFGQKTKVTGAAVGSATHELMQRLTLSDTVTLQDLTQALSRVSASDQVKARVQLEKLLGFFDTELGKLILA
NRDKLRREAPFAMLAEDPASKEDFVVRGIIDGYLLLEDRIVLFDYKTDHFTRPSELKTRYQGQMSLYAKALSQAYQMEKV
DKYLILLGGKDLEVVEV

Nucleotide


Download         Length: 3654 bp        

>NTDB_id=1012138 H1W81_RS02775 WP_179971682.1 513742..517395(+) (rexA) [Streptococcus thermophilus isolate STH_CIRM_67]
ATGTTGACTAAAGCTTTTTTAAGTCCAGCAGAGATTGAGGAACGTATTGCCCAAGAAGCAGCTTCTGACAAGGATCGCAA
GTTAACACCAGAACAGATTGAAGCTATTTACAGTAATGGTACTAATATTTTGGTATCTGCCTCAGCTGGTTCAGGGAAAA
CCTTTGTCATGGTTGAGCGTATCCTTGATATGATTGGACGTGGCGTTGGTATTGATCAACTCTTTATCTCAACCTTTACG
GTAAAAGCTGCAGGTGAGTTAAAGGAGCGTCTGGAAAAGCGGCTGACAAAGCATTTAGGACAGGCAGAGACGGATGAGGA
GCGGGCATTTCTTTCAGACCAGATTGCCAAGATTGGGACGGCTGATATTGGAACCATGGATGCCTTTACCCAGAAATTGG
TCAATCAGTATGGCTATCTCCTGGGTGTGTCACCTACTTTCCGTATCATGACAGACCTTGCTGAGCAGACGCTTATGAAA
AATGAGGTTTATGCTGATCTCTTCAATGATTACATGCAAGGAAAGGATGCCCAACTTTTTCAAAAATTGGTCCGTAATTT
CACTGGACATAGCAAAACTAGCAAGGCTTTTCGTGATTTAGTTTACGATATTTACAGCTTTTCTCAGGCTACTGCAGATC
CTGAAAAATGGCTATGTCAAAATCTCTTGAAAGGACAGATCGAGGCTAAGCCAGAACAGGCTAAAAATGAGCTTTTAGAC
GGTCTTAAAGATGGCTTGTTGGCTGATTTCCTAGCTTTCTTAAGAGACCATTTAGGTATAGCTCAGCGTGAATTTGCCAA
GGCCAAGTATCTGAATAATGTGTCAGACGCCATTATCCTTCTTGAGGGCTCCTTGATTAATGACCAAACTGATATGGAGG
ACCTCCTCAAACAACTATTGACTCTGTCAGGAGGTACTGGTTTGACCAATATGACCCGTCCTAAAGACGAGGAACTCAAG
GCCTACAAGGAAGCATACAACAAGACCAAAAATGAGTTTGTGGCTCAGTTGCGAGAGGTCGATACTCAGCTCACCGTTCT
GGAGGTTTTGACCAAGCATAATGATGATATCCTACCTATGTTGGAGCTACTTCAGTCCTTTGTACTTGATTTTTCGGATC
AGTATTTACAGGCAAAGATTCAGGAAAATACCTTTGAATTCTCGGATATTGCCCACTTTGCTATCCGTATTTTGGAAGAA
AATCCAGAGGTGGCAGTCAGCTACCGGGACCGTTACCATGAAGTTATGGTGGATGAGTATCAGGACAATAGCCATACTCA
AGAACGAATGTTGGAACTTCTATCTAACGGCCATAACCGATTCATGGTGGGAGATATCAAGCAGTCCATTTATCGTTTCC
GTCAGGCAGACCCTCAGATTTTTAATGATAAGTTTCAGCTTTTCCTTGAAAATCCTGATGCAGGTAAGCTGATTCTCCTT
AAGGAGAACTTTCGTAGTCAATCTGAAGTCCTTGATGCGACAAATGGTGTTTTTAGCCACCTCATGGATCAGGAAATCGG
GGACATCCTATATGACAAGACTCATATGTTGGTAGCGGGTAGTCAGAAGCAAAAAGAGCCCCATCCTGAAAATGAAACTG
AGGTTCTGATTTATAATAGTGATGAATCTAGTACGAGTGAGGATGAAGAAGGTCCTGATCAAGCTATCAGCAGCGGTGAG
ATTTCCTTGGTTATCAAAGAAATTATCAAACTTCATGAGCAGGGTGTACGTTTTGAGGACATCACCCTCCTAGCACCGAA
CCGTAACACCTATCTGGACTTGATGGTAAGTTTCGAGGAACACGGGATTCCCTTGGTTCCTGACGAGTATAAGTCAAGCT
ACCTAGAGTCACTAGAAGTTATGATTATGTTGGACACCCTTCGTGCTATCAATAATCCTCTTAACGATTATGCTCTCGTT
GCTCTCCTTCGTTCACCTATGTTTAACTTCAACGAGGATGACCTGACTCGTATCGCAGTTCAGGCTGACAAAGGCCAATT
CTATGATAAGCTTCTTGCAGCTCATACCAAATCAGGTCTTCATCCGGAAGTTGTGATGCAAGGACTTGAAGCCAAGTTGA
CTCTCTTCACAGAGACTCTGGCAGATTGGCGTGACTACAGTAAGTGTCATTCGATTTATGACCTCATTTGGAAGATTTAC
AACGACCGTTTCTATTATGATTACGTCGGAGGTCTTCCACGAGCTGAGCAACGCCAGGCCAATCTTTATGCCCTTGCCTT
GCGTGCTAATGCTTATGAAAAGACAGGATTTAAGGGGCTTTCTCGTTTTATTGGCATGATTGATAAGATTATTGCTAGCG
GTAACGACCTAGAGGAAGTGACAGATTTGGTTCCCAAAAATGCCGTTAGCCTCATGACCATTCACAAGTCCAAGGGGCTA
GAGTTCAAGTATGTCTTTGTCCTGCAGATGAATCGCAAGTTCATTGGTCACAGCAAGGATGGCCTGAGCGGTAAGTATAT
TATCAATCGTGAAAAAGGGCTTGGTATTAAGTATCTAGCTGACCTCAAAGACCAGATAAACACCAATTTGCCTAAGTTAA
ATGTTGTTCTTGAGACCTTGACCTTCCAGGAAAATCGTAGGGAAGAGCGCAGGGCAAGTATTTCAGAAGAGATGCGTCTA
CTCTATGTGGCAATGACACGTGCAGAGAAGAAACTCTACCTAGTTGGTAAGGGAAGTAAGGAAACCTTAACCCAGCAGTA
TGGCACTGATGTCGAAAATAATCGCCTACCAGTGGCTCTACGTGACCAGATTGCTACTTATCAGGATTGGATTATGGCAC
TTGATACTGCTTTTATGAGAAAGGACCTCAAGTTTACTGTTCGCTTTGTTGAGGATGAGGAGTTGACGCCAGAGGCTATT
GGACAGGTTGAAGTCAAGGCAGCAGTAGATGCCGATGATTTATCTAACAATCGTCAGACGGAGGAGATTGAGCGTGCCTT
GACTGTCTTAGAAAGTGTTGAAAAACTCAACCACCTTTATGCACCAGCGATTGACCTACCTTCTGTGCGTACCCCAAGCC
AGCTCAAGACCTTTTACGAACCAATTATGGATACAGAGGGCGTAGATATCATGGATAAGAAAGAGGTAGTGCAACCTCTT
GAGACGGCTAGCACTTTTGAGCTACCAGACTTTGGGCAAAAAACTAAGGTCACTGGAGCTGCAGTTGGTTCAGCAACCCA
TGAACTCATGCAACGCTTGACTCTTTCTGATACAGTGACTCTCCAAGATTTGACTCAGGCACTGAGTCGGGTATCGGCAT
CTGATCAAGTCAAGGCGCGTGTTCAGTTAGAAAAACTTTTAGGTTTCTTTGATACAGAGCTCGGGAAGCTTATTTTGGCC
AACCGTGATAAGTTGCGTCGTGAAGCACCTTTTGCCATGTTGGCAGAAGACCCAGCTAGTAAAGAAGACTTTGTTGTTCG
TGGAATCATTGATGGCTATCTTCTTCTTGAAGACCGTATTGTCCTCTTTGACTACAAGACCGACCACTTCACTCGTCCTA
GTGAGCTTAAGACGCGCTACCAAGGGCAAATGAGCCTCTATGCTAAAGCGCTTAGCCAAGCCTATCAAATGGAAAAGGTC
GACAAATATCTTATCCTCTTGGGTGGAAAGGACTTAGAAGTTGTAGAAGTATAA

Domains

Predicted by InterProScan.

PD-(D/E)XK nuclease superfamily (PDDEXK_1)

(1059-1198)

UvrD/REP helicase N-terminal domain (UvrD-helicase)

(28-464)

UvrD-like helicase C-terminal domain (UvrD_C)

(478-894)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rexA Streptococcus pneumoniae R6

50.612

100

0.509

Multiple sequence alignment