Detailed information NTG1011457

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: UXQ63_RS14195
• Genome accession: NZ_CP158481
• Coordinates: 2799100..2799987 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain BSN88
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2794100..2804987

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXQ63_RS14165 (UXQ63_014165)	-	2794119..2794211 (+)	93	WP_010956583.1	hypothetical protein	-
UXQ63_RS14170 (UXQ63_014170)	-	2794319..2794816 (-)	498	WP_001065268.1	glutathione peroxidase	-
UXQ63_RS14175 (UXQ63_014175)	-	2794826..2795086 (-)	261	WP_001789910.1	hypothetical protein	-
UXQ63_RS14180 (UXQ63_014180)	-	2795468..2795581 (-)	114	WP_001791776.1	hypothetical protein	-
UXQ63_RS14185 (UXQ63_014185)	-	2796240..2798240 (-)	2001	WP_000776751.1	ABC transporter permease	-
UXQ63_RS14190 (UXQ63_014190)	-	2798237..2798992 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
UXQ63_RS14195 (UXQ63_014195)	braS	2799100..2799987 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
UXQ63_RS14200 (UXQ63_014200)	braR	2799998..2800663 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
UXQ63_RS14205 (UXQ63_014205)	-	2800689..2800889 (-)	201	WP_000604728.1	hypothetical protein	-
UXQ63_RS14210 (UXQ63_014210)	-	2801087..2802511 (+)	1425	WP_000953744.1	alkaline phosphatase	-
UXQ63_RS14215 (UXQ63_014215)	-	2802571..2802672 (-)	102	WP_000731972.1	SE2200 family small protein	-
UXQ63_RS14220 (UXQ63_014220)	-	2802794..2803249 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
UXQ63_RS14225 (UXQ63_014225)	-	2803494..2804255 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1011457 UXQ63_RS14195 WP_000143419.1 2799100..2799987(-) (braS) [Staphylococcus aureus strain BSN88]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1011457 UXQ63_RS14195 WP_000143419.1 2799100..2799987(-) (braS) [Staphylococcus aureus strain BSN88]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997