Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   H1W90_RS06725 Genome accession   NZ_LR822033
Coordinates   1303082..1303726 (-) Length   214 a.a.
NCBI ID   WP_002951384.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1048     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1298082..1308726
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W90_RS06700 (STHERMO_1498) - 1300183..1301181 (-) 999 WP_180481056.1 NAD(P)/FAD-dependent oxidoreductase -
  H1W90_RS06705 (STHERMO_1499) trmD 1301183..1301902 (-) 720 WP_011226285.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  H1W90_RS06710 (STHERMO_1500) rimM 1301892..1302410 (-) 519 WP_180481057.1 ribosome maturation factor RimM -
  H1W90_RS06725 (STHERMO_1502) vraR 1303082..1303726 (-) 645 WP_002951384.1 response regulator transcription factor Regulator
  H1W90_RS06730 (STHERMO_1503) - 1303716..1304726 (-) 1011 WP_011226288.1 sensor histidine kinase -
  H1W90_RS06735 (STHERMO_1504) liaF 1304723..1305421 (-) 699 WP_011226289.1 cell wall-active antibiotics response protein LiaF -
  H1W90_RS10100 (STHERMO_1505) - 1305676..1305843 (-) 168 WP_224103618.1 potassium channel family protein -
  H1W90_RS06745 (STHERMO_1508) stkP/pknB 1306480..1308351 (-) 1872 WP_176243308.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24048.39 Da        Isoelectric Point: 4.5864

>NTDB_id=1010943 H1W90_RS06725 WP_002951384.1 1303082..1303726(-) (vraR) [Streptococcus thermophilus isolate STH_CIRM_1048]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=1010943 H1W90_RS06725 WP_002951384.1 1303082..1303726(-) (vraR) [Streptococcus thermophilus isolate STH_CIRM_1048]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGACCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTAGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTAAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCATGATAGTCACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACCGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379

Multiple sequence alignment