Detailed information NTG1009870

Bioinformatically predicted

Overview

• Name: ccrB
• Type: Machinery gene
• Locus tag: Q6165_RS00260
• Genome accession: NZ_CP158131
• Coordinates: 57009..58637 (-)
• Length: 542 a.a.
• NCBI ID: WP_001186602.1
• Uniprot ID: Q9XB94
• Organism: Staphylococcus aureus strain BSN51
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	38668..60008	57009..58637	within	0

Gene organization within MGE regions

Location: 38668..60008

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q6165_RS00160 (Q6165_00160)	mecA	38668..40677 (-)	2010	WP_001801873.1	PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA	-
Q6165_RS00165 (Q6165_00165)	mecR1	40774..42531 (+)	1758	WP_000952923.1	beta-lactam sensor/signal transducer MecR1	-
Q6165_RS00170 (Q6165_00170)	mecI	42531..42902 (+)	372	WP_000369214.1	mecA-type methicillin resistance repressor MecI	-
Q6165_RS00175 (Q6165_00175)	psm-mec	42987..43055 (-)	69	WP_014532405.1	phenol-soluble modulin PSM-mec	-
Q6165_RS00180 (Q6165_00180)	-	43389..44519 (+)	1131	WP_010922808.1	ROK family transcriptional regulator	-
Q6165_RS00185 (Q6165_00185)	cstB	44633..45967 (-)	1335	Protein_34	persulfide dioxygenase-sulfurtransferase CstB	-
Q6165_RS00190 (Q6165_00190)	-	46000..47064 (-)	1065	WP_000438836.1	DsrE/DsrF/DrsH-like family protein	-
Q6165_RS00195 (Q6165_00195)	cstR	47200..47460 (+)	261	WP_000220507.1	persulfide-sensing transcriptional repressor CstR	-
Q6165_RS00200 (Q6165_00200)	-	47460..48098 (+)	639	Protein_37	sulfite exporter TauE/SafE family protein	-
Q6165_RS00205 (Q6165_00205)	-	48443..49105 (-)	663	WP_001092058.1	class I SAM-dependent methyltransferase	-
Q6165_RS00210	-	49497..49556 (+)	60	WP_010959190.1	erythromycin resistance leader peptide	-
Q6165_RS00215 (Q6165_00210)	erm(A)	49614..50345 (+)	732	WP_001072201.1	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A)	-
Q6165_RS00220 (Q6165_00215)	-	50471..51253 (-)	783	WP_000067268.1	aminoglycoside nucleotidyltransferase ANT(9)-Ia	-
Q6165_RS00225 (Q6165_00220)	-	51404..51781 (-)	378	WP_000361059.1	DUF6262 family protein	-
Q6165_RS00230 (Q6165_00225)	-	51788..53680 (-)	1893	WP_001557544.1	site-specific integrase	-
Q6165_RS00235 (Q6165_00230)	-	53677..54762 (-)	1086	WP_000868132.1	tyrosine-type recombinase/integrase	-
Q6165_RS00240 (Q6165_00235)	-	54881..55198 (-)	318	WP_000659050.1	JAB domain-containing protein	-
Q6165_RS00245 (Q6165_00240)	-	55219..55725 (-)	507	WP_001092169.1	DUF1643 domain-containing protein	-
Q6165_RS00250 (Q6165_00245)	-	55743..56054 (-)	312	WP_000700853.1	DUF960 family protein	-
Q6165_RS00255 (Q6165_00250)	-	56141..56491 (-)	351	WP_000859155.1	SAUGI family uracil-DNA glycosylase inhibitor	-
Q6165_RS00260 (Q6165_00255)	ccrB	57009..58637 (-)	1629	WP_001186602.1	recombinase family protein	Machinery gene
Q6165_RS00265 (Q6165_00260)	ccrA	58659..60008 (-)	1350	WP_000815646.1	recombinase family protein	Machinery gene

Sequence

Protein

• Length: 542 a.a.
• Molecular weight: 62664.84 Da
• Isoelectric Point: 9.8600

>NTDB_id=1009870 Q6165_RS00260 WP_001186602.1 57009..58637(-) (ccrB) [Staphylococcus aureus strain BSN51]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI

Nucleotide

• Length: 1629 bp

>NTDB_id=1009870 Q6165_RS00260 WP_001186602.1 57009..58637(-) (ccrB) [Staphylococcus aureus strain BSN51]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG

Domains

Predicted by InterproScan.

• Ogr/Delta-like zinc finger (Ogr_Delta) (301-356)

• Resolvase, N terminal domain (Resolvase) (11-156)

• Recombinase (Recombinase) (180-280)

3D structure

• AlphaFold DB: Q9XB94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrB	Staphylococcus aureus N315	100	100	1