Detailed information NTG1009217

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: H0504_RS01905
• Genome accession: NZ_LR822011
• Coordinates: 363059..365299 (+)
• Length: 746 a.a.
• NCBI ID: WP_011227470.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_23
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 358059..370299

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0504_RS01880 (STHERMO_0400)	-	359359..359628 (-)	270	WP_011226404.1	GIY-YIG nuclease family protein	-
H0504_RS01885 (STHERMO_0401)	-	359632..360396 (-)	765	WP_011226403.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
H0504_RS10075	-	360446..360895 (-)	450	WP_311316658.1	hypothetical protein	-
H0504_RS09465 (STHERMO_0403)	-	360778..361311 (-)	534	WP_011226401.1	polysaccharide deacetylase family protein	-
H0504_RS01895 (STHERMO_0404)	-	361511..362266 (+)	756	WP_002948862.1	lysophospholipid acyltransferase family protein	-
H0504_RS01900 (STHERMO_0405)	comEA	362374..363069 (+)	696	WP_011226400.1	helix-hairpin-helix domain-containing protein	Machinery gene
H0504_RS01905 (STHERMO_0406)	comEC/celB	363059..365299 (+)	2241	WP_011227470.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
H0504_RS01910 (STHERMO_0407)	-	365385..366647 (+)	1263	WP_022096991.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
H0504_RS01915 (STHERMO_0408)	-	366713..367258 (+)	546	WP_041828309.1	GNAT family N-acetyltransferase	-
H0504_RS01920 (STHERMO_0409)	spxR	367251..368531 (+)	1281	WP_179971766.1	CBS-HotDog domain-containing transcription factor SpxR	-
H0504_RS01925 (STHERMO_0410)	-	368575..369435 (+)	861	WP_011226395.1	methionyl aminopeptidase	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84850.87 Da
• Isoelectric Point: 9.9608

>NTDB_id=1009217 H0504_RS01905 WP_011227470.1 363059..365299(+) (comEC/celB) [Streptococcus thermophilus isolate STH_CIRM_23]
MWLKKAPINLFSLALLIVALYFTIFVSNFYAIGTFVFLMICFLRHHWKNRAALKLVGLIGGFFLVYFLFLYHIAIMQDKQ
TPAEIHQVTLVADTLSVNGERLSAIGKSNGQTYQVFYRLKSDKEQHFFKTTSQTLVLKGKIKLSSATGQRNFQGFDYQSY
LASQGIYRIAQIDRLEHVVIPKSISPIAFFHQLRRKALVHIQTHFPNPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKNYILAILLPFSIFYGLMTGWTASVLRSLIQSLLAECGIKKLNNMGITLLLFFLV
LPHFLLTVGGVLSCSYAFLLCLFNFEEMPSFKKSIYMSLVLSLGTLPFLTYYYGTFQPLSLILTAIFSLVFDSFLLPVLT
VLFTLSGMVIFSQFNTLFEWMEFFLTWVQSWGVQPLILGKPSLFQFVSMIFVLVLLFDFWKKPQFRISLLMIFSLLMVWV
KHPLINEVTVVDVGQGDSIFLRSMKGETVLIDVGGKVTFGSKEKWQEGSQTSNAEKTLIPYLQARGVSQIDYLVLTHTDT
DHIGDLEVVAKRFKIKKICVSEGALTKPSFAKRIRFLKCPVRTLKAGDKLPMMGSNLQVLYPNKIGNGGNNDSLVLYGKL
LGTSFLFTGDLEKEGEEELMTSYPNLKVRVLKAGHHGSKGSSSEAFLDQLKPSLALVSAGENNRYKHPNDETLERFKERH
IKVLRTDQDGAIRFKGWFQLSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=1009217 H0504_RS01905 WP_011227470.1 363059..365299(+) (comEC/celB) [Streptococcus thermophilus isolate STH_CIRM_23]
ATGTGGCTTAAAAAAGCTCCAATCAATCTTTTTTCCCTAGCGCTTTTAATAGTTGCTCTTTATTTTACTATTTTTGTATC
TAATTTCTATGCTATTGGGACTTTTGTCTTTCTGATGATATGTTTTTTGAGGCATCATTGGAAGAATAGAGCAGCTCTAA
AGTTGGTGGGACTTATAGGTGGTTTCTTTTTGGTCTACTTTTTATTTTTATACCATATAGCTATCATGCAAGATAAACAA
ACTCCTGCTGAAATTCATCAGGTGACACTGGTTGCAGATACGCTCTCAGTTAATGGTGAGCGATTATCAGCAATCGGGAA
GTCAAATGGACAAACCTATCAGGTCTTTTACCGGCTAAAATCTGATAAGGAGCAGCATTTTTTTAAGACTACTAGTCAAA
CGCTTGTTTTAAAAGGGAAAATAAAGTTGTCCTCGGCAACTGGTCAACGTAATTTTCAAGGATTTGATTATCAGTCTTAT
CTAGCTAGTCAGGGCATTTATAGGATTGCTCAGATTGACCGTCTGGAACATGTCGTAATCCCAAAATCGATATCTCCAAT
AGCTTTTTTTCATCAATTGAGGAGGAAGGCTCTAGTTCATATTCAGACGCATTTTCCTAATCCGATGAGACACTACATGA
CAGGACTGCTCTTTGGGTATTTGGACAAGGAGTTTGATGAGCAGAGTCAACTCTACACTAGCTTGGGGATTATTCATCTT
TTTGCGCTATCGGGTATGCAGGTTGGATTTTTTCTTGGCTGGTTTCGCTATGGACTTCTCCGTTTGGGGCTTCCCAAAAA
TTATATCCTTGCTATCTTATTACCTTTTTCGATTTTCTATGGCTTAATGACTGGTTGGACGGCTTCGGTCTTACGTTCTT
TGATTCAAAGCCTCTTGGCTGAGTGTGGTATTAAAAAACTGAACAATATGGGCATAACGCTACTTCTATTTTTTCTAGTC
TTGCCTCATTTTCTTTTAACGGTAGGAGGTGTTTTAAGTTGTTCTTATGCCTTCTTGTTGTGTTTATTTAATTTTGAGGA
GATGCCGTCCTTTAAAAAGTCAATTTATATGAGTTTAGTATTGAGTCTTGGGACTTTGCCTTTTTTGACCTACTATTATG
GAACTTTTCAACCATTGAGTTTGATTCTGACGGCAATCTTCTCTCTAGTTTTTGATAGCTTTCTCTTACCTGTCTTAACA
GTACTTTTTACACTTTCAGGAATGGTAATTTTTTCTCAATTTAACACACTTTTTGAATGGATGGAGTTCTTTTTGACTTG
GGTACAATCTTGGGGAGTCCAGCCATTGATTTTAGGAAAACCTAGCTTGTTTCAGTTTGTCTCAATGATATTTGTATTGG
TTTTGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGAATATCCCTCTTGATGATTTTTAGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAATAAATGAAGTAACGGTGGTCGACGTTGGTCAAGGAGATAGTATTTTTTTAAGGAGTATGAAAGGTGA
AACGGTCCTAATAGATGTAGGTGGCAAGGTGACTTTCGGCTCTAAGGAAAAATGGCAAGAGGGGAGCCAGACGAGTAATG
CGGAGAAAACCTTAATTCCCTATCTACAGGCAAGGGGAGTGTCTCAAATTGACTATCTGGTTCTGACTCATACGGATACA
GACCATATTGGTGATTTGGAGGTAGTGGCTAAACGGTTTAAGATTAAGAAAATTTGTGTCAGTGAGGGGGCTTTGACTAA
GCCTAGTTTTGCCAAACGTATTCGATTTCTTAAATGTCCCGTTCGCACTTTAAAGGCTGGTGATAAGCTGCCTATGATGG
GAAGTAACCTACAGGTTCTTTATCCCAATAAAATTGGTAATGGTGGTAACAATGATTCACTTGTTCTCTATGGAAAGTTA
TTGGGAACCAGTTTTCTATTTACTGGTGATTTGGAAAAAGAAGGAGAAGAGGAATTGATGACTAGCTATCCAAATTTAAA
AGTAAGGGTCCTCAAAGCAGGACATCACGGTTCTAAAGGCTCTTCATCAGAAGCTTTTTTGGATCAGCTAAAGCCATCAC
TTGCTCTTGTCTCAGCAGGTGAAAATAATCGTTATAAGCATCCAAATGATGAAACATTAGAGCGTTTCAAAGAACGTCAC
ATTAAGGTTTTACGCACAGACCAGGATGGTGCCATTCGGTTTAAGGGATGGTTCCAACTATCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterProScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-699)

• Competence protein (Competence) (216-462)

• Domain of unknown function (DUF4131) (DUF4131) (29-170)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	47.587	100	0.476
comEC/celB	Streptococcus mitis SK321	46.72	100	0.468
comEC/celB	Streptococcus pneumoniae TIGR4	45.783	100	0.458
comEC/celB	Streptococcus pneumoniae D39	45.515	100	0.456
comEC/celB	Streptococcus pneumoniae Rx1	45.515	100	0.456
comEC/celB	Streptococcus pneumoniae R6	45.515	100	0.456
comEC	Lactococcus lactis subsp. cremoris KW2	45.379	97.185	0.441