Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ABKA15_RS07560 Genome accession   NZ_CP157941
Coordinates   1544354..1545109 (-) Length   251 a.a.
NCBI ID   WP_049514496.1    Uniprot ID   A0A7L8W6J2
Organism   Streptococcus sp. KHUD_010     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1539354..1550109
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABKA15_RS07540 (ABKA15_07535) - 1539786..1541018 (-) 1233 WP_049514499.1 cysteine desulfurase -
  ABKA15_RS07545 (ABKA15_07540) sufD 1541034..1542296 (-) 1263 WP_049514498.1 Fe-S cluster assembly protein SufD -
  ABKA15_RS07550 (ABKA15_07545) sufC 1542336..1543106 (-) 771 WP_049514506.1 Fe-S cluster assembly ATPase SufC -
  ABKA15_RS07555 (ABKA15_07550) - 1543197..1544363 (-) 1167 WP_003028442.1 MraY family glycosyltransferase -
  ABKA15_RS07560 (ABKA15_07555) mecA 1544354..1545109 (-) 756 WP_049514496.1 adaptor protein MecA Regulator
  ABKA15_RS07565 (ABKA15_07560) - 1545246..1546190 (-) 945 WP_350015336.1 IS30 family transposase -
  ABKA15_RS07570 (ABKA15_07565) - 1546283..1547125 (-) 843 WP_049514707.1 undecaprenyl-diphosphate phosphatase -
  ABKA15_RS07575 (ABKA15_07570) - 1547192..1549081 (-) 1890 WP_350015337.1 DUF2207 domain-containing protein -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 29164.96 Da        Isoelectric Point: 4.1439

>NTDB_id=1009135 ABKA15_RS07560 WP_049514496.1 1544354..1545109(-) (mecA) [Streptococcus sp. KHUD_010]
MEMKQISDTTIKITIKLEDLEERGMEMADFLVPQEKTEEFFYAILDELEMPESFLDNGMLSFRVTPKPDRLDVFVTKSKI
DKNLNFEDLADLPDVEELSQMSPDEFLKTLEKNIFEKSKDDMETVRSLETAEADDNTSTSDMEEQDENSDELTQKYIYYI
LKFSSLKEAIIFSKTVDYAVNTSELYKMDDHYYLTILVDIEGHPKRYPAWLLASMREHAEDTDVTRAVLQEHGYLLLVNE
AVASLKKVKCL

Nucleotide


Download         Length: 756 bp        

>NTDB_id=1009135 ABKA15_RS07560 WP_049514496.1 1544354..1545109(-) (mecA) [Streptococcus sp. KHUD_010]
ATGGAAATGAAGCAAATTAGTGATACAACGATTAAGATCACAATAAAATTAGAAGATTTAGAAGAACGTGGAATGGAGAT
GGCAGATTTTCTTGTTCCGCAAGAAAAGACAGAAGAGTTTTTCTATGCAATTTTAGATGAGTTGGAAATGCCAGAGAGTT
TTTTGGATAACGGTATGCTCAGTTTTCGTGTAACTCCTAAACCAGACCGACTGGATGTGTTTGTCACCAAGTCTAAGATT
GATAAGAATCTGAACTTCGAGGATTTGGCGGATTTGCCAGATGTAGAAGAGCTGTCTCAAATGTCTCCAGATGAATTTTT
AAAGACATTAGAAAAAAATATTTTTGAGAAAAGTAAAGATGATATGGAGACTGTTCGTTCTTTGGAAACGGCGGAAGCAG
ACGATAACACAAGCACTTCTGATATGGAAGAACAAGATGAAAATAGTGACGAGCTCACACAAAAATATATCTATTACATT
TTGAAATTTTCCAGCCTGAAAGAAGCAATTATTTTTTCTAAAACAGTAGATTATGCTGTCAATACTTCGGAGTTGTACAA
AATGGACGATCACTATTATTTGACAATTCTGGTGGATATTGAGGGACACCCGAAGCGTTATCCAGCTTGGCTCCTTGCCT
CTATGCGTGAACATGCAGAAGACACGGATGTGACGAGAGCTGTTTTGCAAGAGCACGGTTATTTATTGCTTGTCAACGAG
GCGGTTGCCAGTCTTAAAAAGGTTAAATGCTTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7L8W6J2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

65.726

98.805

0.649
  mecA Streptococcus pneumoniae D39

65.726

98.805

0.649
  mecA Streptococcus pneumoniae R6

65.726

98.805

0.649
  mecA Streptococcus pneumoniae TIGR4

65.323

98.805

0.645
  mecA Streptococcus mutans UA159

49.194

98.805

0.486
  mecA Streptococcus thermophilus LMD-9

45.49

100

0.462
  mecA Streptococcus thermophilus LMG 18311

45.098

100

0.458

Multiple sequence alignment