Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   H0501_RS06750 Genome accession   NZ_LR822008
Coordinates   1305792..1306436 (-) Length   214 a.a.
NCBI ID   WP_002951384.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_18     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1300792..1311436
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0501_RS06725 (STHERMO_1491) - 1302893..1303891 (-) 999 WP_014608529.1 NAD(P)/FAD-dependent oxidoreductase -
  H0501_RS06730 (STHERMO_1492) trmD 1303893..1304612 (-) 720 WP_011226285.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  H0501_RS06735 (STHERMO_1493) rimM 1304602..1305120 (-) 519 WP_011226286.1 ribosome maturation factor RimM -
  H0501_RS06750 (STHERMO_1494) vraR 1305792..1306436 (-) 645 WP_002951384.1 response regulator transcription factor Regulator
  H0501_RS06755 (STHERMO_1495) - 1306426..1307436 (-) 1011 WP_011227402.1 sensor histidine kinase -
  H0501_RS06760 (STHERMO_1496) liaF 1307433..1308131 (-) 699 WP_011226289.1 cell wall-active antibiotics response protein LiaF -
  H0501_RS10085 (STHERMO_1497) - 1308386..1308553 (-) 168 WP_014608530.1 potassium channel family protein -
  H0501_RS06770 (STHERMO_1500) stkP/pknB 1309190..1311061 (-) 1872 WP_014621795.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24048.39 Da        Isoelectric Point: 4.5864

>NTDB_id=1008944 H0501_RS06750 WP_002951384.1 1305792..1306436(-) (vraR) [Streptococcus thermophilus isolate STH_CIRM_18]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=1008944 H0501_RS06750 WP_002951384.1 1305792..1306436(-) (vraR) [Streptococcus thermophilus isolate STH_CIRM_18]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGACCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTGGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTCAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCATGATAGTCACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACCGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379