NTDB

Overview

Name	cclA/cilC	Type	Machinery gene
Locus tag	FGL05_RS06415	Genome accession	NZ_LR594044
Coordinates	1316754..1317404 (+)	Length	216 a.a.
NCBI ID	WP_020916359.1	Uniprot ID	A0AB33AKJ9
Organism	Streptococcus lutetiensis strain NCTC8796
Function	processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1311754..1322404

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL05_RS06390 (NCTC8796_01356)	-	1313353..1314168 (-)	816	WP_228380506.1	hypothetical protein	-
FGL05_RS09515 (NCTC8796_01357)	-	1314208..1314384 (-)	177	WP_231853159.1	hypothetical protein	-
FGL05_RS06395 (NCTC8796_01358)	-	1314399..1314779 (-)	381	WP_020916363.1	rhodanese-like domain-containing protein	-
FGL05_RS06400 (NCTC8796_01359)	-	1314790..1315758 (-)	969	WP_111712661.1	ROK family glucokinase	-
FGL05_RS06405 (NCTC8796_01360)	-	1315751..1315960 (-)	210	WP_006531568.1	YqgQ family protein	-
FGL05_RS06410 (NCTC8796_01361)	-	1316091..1316615 (-)	525	WP_020916360.1	Dps family protein	-
FGL05_RS06415 (NCTC8796_01362)	cclA/cilC	1316754..1317404 (+)	651	WP_020916359.1	A24 family peptidase	Machinery gene
FGL05_RS06420 (NCTC8796_01363)	-	1317492..1318838 (+)	1347	WP_138122261.1	Nramp family divalent metal transporter	-
FGL05_RS06425 (NCTC8796_01365)	trpA	1318874..1319657 (-)	784	Protein_1305	tryptophan synthase subunit alpha	-
FGL05_RS06430 (NCTC8796_01366)	trpB	1319661..1320794 (-)	1134	Protein_1306	tryptophan synthase subunit beta	-
FGL05_RS06435 (NCTC8796_01367)	-	1320868..1321449 (-)	582	WP_058833199.1	phosphoribosylanthranilate isomerase	-
FGL05_RS06440 (NCTC8796_01368)	trpC	1321436..1322176 (-)	741	WP_058833333.1	indole-3-glycerol phosphate synthase TrpC	-

Sequence

Protein

Download Length: 216 a.a. Molecular weight: 24600.50 Da Isoelectric Point: 5.5569

                                >NTDB_id=1005583 FGL05_RS06415 WP_020916359.1 1316754..1317404(+) (cclA/cilC) [Streptococcus lutetiensis strain NCTC8796]

MDTFLFFFLGASLASFIGLVVDRFLEESILFPASHCNTCGKQLRPLDMIPVLSQIFNHSRCHFCKSKIPLWYGIFEFVCG

LATALYYHDIIAPSSLFIFFFSMTLSLYDLKNQSFPLLIWLLPSASLLLFLPLNTVSIILLLLGIIAELFDIKIGSGDFF

YLASLSLFLDLESILWIVELGSLVGILYCLFDKNKRIPFIPFLFLGYLLVIIFKCD

Nucleotide

Download Length: 651 bp

                                >NTDB_id=1005583 FGL05_RS06415 WP_020916359.1 1316754..1317404(+) (cclA/cilC) [Streptococcus lutetiensis strain NCTC8796]

ATGGACACTTTTTTATTCTTTTTTCTTGGAGCATCGCTTGCTTCATTTATCGGATTAGTTGTTGATCGTTTTCTAGAGGA

ATCTATTTTATTTCCTGCTAGTCATTGTAATACCTGTGGTAAACAACTGAGACCGCTAGACATGATTCCAGTTCTTTCTC

AGATTTTTAATCATTCTCGCTGCCATTTTTGCAAAAGTAAAATACCTTTATGGTATGGCATTTTTGAATTTGTCTGTGGG

CTCGCAACTGCTCTTTATTACCACGATATCATAGCACCATCTAGTCTCTTTATTTTCTTCTTTAGCATGACACTTAGTTT

ATATGATTTAAAAAACCAGTCCTTTCCTCTATTAATCTGGTTACTACCCAGTGCTTCTTTACTCCTTTTTCTTCCTCTTA

ATACGGTAAGTATTATTCTTCTTTTACTTGGGATCATAGCTGAGCTTTTTGACATAAAAATCGGTAGCGGTGATTTTTTC

TACCTAGCCAGTTTGAGTCTTTTTCTTGATTTGGAGAGCATTTTATGGATTGTTGAACTGGGTTCTTTGGTAGGAATTCT

GTATTGCCTTTTTGATAAAAACAAACGCATTCCCTTTATTCCTTTTCTATTTTTAGGCTATCTTTTAGTTATAATTTTTA

AGTGTGATTAA

Domains

Predicted by InterProScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(9-88)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0AB33AKJ9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
cclA/cilC	Streptococcus pneumoniae TIGR4	43.256	99.537	0.431
cclA/cilC	Streptococcus pneumoniae Rx1	42.791	99.537	0.426
cclA/cilC	Streptococcus pneumoniae D39	42.791	99.537	0.426
cclA/cilC	Streptococcus pneumoniae R6	42.791	99.537	0.426
cclA/cilC	Streptococcus mitis SK321	42.857	97.222	0.417
cclA/cilC	Streptococcus mitis NCTC 12261	41.86	99.537	0.417

Detailed information NTG1005583