Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   EL139_RS06255 Genome accession   NZ_LR134316
Coordinates   1221687..1222328 (+) Length   213 a.a.
NCBI ID   WP_014612503.1    Uniprot ID   A0A9X9QU89
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1216687..1227328
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL139_RS06235 (NCTC6181_01269) - 1217242..1217982 (+) 741 WP_111717293.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  EL139_RS06240 (NCTC6181_01270) pknB 1217979..1219874 (+) 1896 WP_111717291.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  EL139_RS06245 (NCTC6181_01271) liaF 1220001..1220693 (+) 693 WP_111717289.1 cell wall-active antibiotics response protein LiaF -
  EL139_RS06250 (NCTC6181_01272) - 1220690..1221694 (+) 1005 WP_003061197.1 sensor histidine kinase -
  EL139_RS06255 (NCTC6181_01273) vraR 1221687..1222328 (+) 642 WP_014612503.1 response regulator transcription factor Regulator
  EL139_RS06260 (NCTC6181_01274) - 1222365..1223765 (+) 1401 WP_111717286.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  EL139_RS06265 (NCTC6181_01275) - 1223765..1224124 (+) 360 WP_111717284.1 S1 RNA-binding domain-containing protein -
  EL139_RS06270 (NCTC6181_01276) cysK 1224276..1225211 (-) 936 WP_012767420.1 cysteine synthase A -
  EL139_RS06275 (NCTC6181_01277) - 1225315..1225953 (-) 639 WP_111717282.1 YigZ family protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23806.38 Da        Isoelectric Point: 4.7966

>NTDB_id=1001372 EL139_RS06255 WP_014612503.1 1221687..1222328(+) (vraR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181]
MSNIRVILVDDHEMVRMGLKSFLNLQPDIDVIGEASNGREGVELALALKPDVLVMDLVMPELGGVEATLEILDKWKDAKV
LVLTSYLDNEKIYPVIDAGAKGYMLKTSSAAEILNAIRKVSKGELAIETEVDKKIKAHDQHPDLHEELTAREYDILHLLA
KGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFRHHLVPQDDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=1001372 EL139_RS06255 WP_014612503.1 1221687..1222328(+) (vraR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181]
ATGAGTAACATAAGAGTGATACTAGTGGATGATCATGAAATGGTCCGTATGGGACTTAAAAGTTTTTTGAATTTACAACC
AGATATCGACGTTATTGGCGAAGCTTCTAATGGACGTGAGGGAGTTGAGTTGGCCTTAGCCTTAAAACCAGATGTGCTGG
TTATGGATTTGGTAATGCCAGAATTAGGTGGGGTTGAGGCGACTTTGGAAATCCTCGATAAGTGGAAAGATGCCAAAGTA
TTGGTCTTGACTTCTTATTTGGACAATGAGAAAATTTACCCTGTCATTGATGCTGGTGCTAAAGGTTACATGTTAAAGAC
TTCTAGTGCAGCCGAAATTCTAAATGCTATTCGGAAAGTTTCAAAAGGTGAATTGGCCATTGAAACAGAGGTAGACAAAA
AAATTAAAGCGCATGACCAACACCCTGATTTGCATGAAGAGCTAACCGCGCGCGAGTATGATATTCTACATCTTTTAGCT
AAAGGGTATGATAATCAAACTATAGCGGATGAACTTTTCATCTCCTTGAAAACCGTTAAAACGCATGTGTCTAATATTCT
TGCTAAGCTAGAAGTTGATGACCGAACTCAAGCTGTTGTATACGCTTTCCGACACCATTTAGTCCCCCAAGATGATAATT
AG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A9X9QU89

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.691

97.183

0.502
  degU Bacillus subtilis subsp. subtilis str. 168

35.398

100

0.376