Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   EL092_RS01315 Genome accession   NZ_LR134291
Coordinates   276512..278845 (+) Length   777 a.a.
NCBI ID   WP_011999790.1    Uniprot ID   A8AUW9
Organism   Streptococcus gordonii strain NCTC7868     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 271512..283845
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL092_RS01295 (NCTC7868_00255) lepB 273957..274559 (-) 603 WP_011999786.1 signal peptidase I -
  EL092_RS01300 (NCTC7868_00256) rnhC 274563..275453 (-) 891 WP_011999787.1 ribonuclease HIII -
  EL092_RS01305 (NCTC7868_00257) - 275603..275908 (+) 306 WP_008808274.1 hypothetical protein -
  EL092_RS01310 (NCTC7868_00258) - 275908..276456 (+) 549 WP_041789851.1 CvpA family protein -
  EL092_RS01315 (NCTC7868_00259) mutS/mutS2 276512..278845 (+) 2334 WP_011999790.1 endonuclease MutS2 Machinery gene
  EL092_RS01320 (NCTC7868_00260) - 278856..279500 (+) 645 WP_011999791.1 GNAT family N-acetyltransferase -
  EL092_RS01325 (NCTC7868_00261) - 279601..281019 (+) 1419 WP_011999792.1 C69 family dipeptidase -
  EL092_RS01330 (NCTC7868_00262) trxA 281104..281418 (+) 315 WP_011999793.1 thioredoxin -
  EL092_RS01335 (NCTC7868_00263) - 281580..282098 (-) 519 WP_011999794.1 DUF4865 family protein -
  EL092_RS01340 (NCTC7868_00264) - 282207..282953 (+) 747 WP_011999795.1 LysR family transcriptional regulator -
  EL092_RS01345 (NCTC7868_00265) - 283053..283460 (+) 408 WP_011999796.1 polyketide cyclase -

Sequence

Protein


Download         Length: 777 a.a.        Molecular weight: 87380.98 Da        Isoelectric Point: 5.9561

>NTDB_id=1000169 EL092_RS01315 WP_011999790.1 276512..278845(+) (mutS/mutS2) [Streptococcus gordonii strain NCTC7868]
MNTKILETLEFNKIKDLFQGSLQTEQGKLELQVLQPTTKKEAIERAFLEVTDMEQILVEDPHFHLAATKDITAISKRLEL
DGDLNIEELLVLKKVLRVSHDLVTFYNDLENVRLQELNRIFENLVDFPAIQGSLLAVNDGGFIESFASEELGRIRRKIQE
NESKVRDLLQEILKNKGDMLADQVVASRNGRNVLPVKNTYRNRIPGVVHDISASGTTIYIEPRAVVNLNEEISNYKADER
YELLRILQELSAMIRPHAAEIANNAWIIGHLDLVMAKLAFMRERGAVVPAISDTQAIQLLQVRHPLIQNAVANDLHFGPD
LTEIVITGPNTGGKTIMLKTLGLAQIMAQSGLPILADKGSRVGIFSQIFADIGDEQSIEQSLSTFSSHMTNIVSILEQVD
SESLVLLDELGAGTDPQEGAALAIAILEDLRLRQIKTMATTHYPELKAYGIETDWVENASMEFDTDSLRPTYRFMQGVPG
RSNAFEIARRLGLSEVIVSHAQEQTNTDSDVNQIIERLEEQTLESRKRLDNIREVEQENLKFNRALKKLYNEFNREKETE
LNKARLEAQEIVDLALSESESILKNLHAKSSLKPHEIIEAKAQLKKLAPETVDLSKNKVLKQAKKNRAPKVGDDILVTSY
GQRGTLVKLLKDGRWEAQVGLIKMTLEEQEFNLLKAEKEQQPKRKQVNVVKRANTAGPRARLDLRGKRYEEAMKELDEFI
DQALLNNMAQVDIIHGIGTGVIREGVNKYLRRNKHVKSFGYAPQNAGGSGATIVIFK

Nucleotide


Download         Length: 2334 bp        

>NTDB_id=1000169 EL092_RS01315 WP_011999790.1 276512..278845(+) (mutS/mutS2) [Streptococcus gordonii strain NCTC7868]
ATGAATACAAAAATATTAGAAACCTTAGAATTTAATAAAATAAAAGACTTATTCCAAGGCTCTTTACAAACGGAGCAGGG
GAAATTAGAATTACAAGTTTTACAGCCGACCACAAAAAAAGAGGCGATTGAGAGAGCCTTTTTGGAAGTTACGGATATGG
AGCAGATTTTAGTAGAAGATCCGCATTTTCATTTGGCAGCAACCAAGGATATCACTGCTATTAGCAAGCGTTTGGAGCTT
GATGGTGATCTGAATATCGAGGAATTGCTTGTTTTAAAAAAGGTTTTGCGCGTTTCGCATGACTTGGTTACTTTTTATAA
TGATTTAGAAAATGTTCGACTTCAAGAATTGAATCGTATTTTTGAAAATTTAGTCGACTTCCCTGCTATTCAAGGGAGTC
TTCTAGCTGTCAACGACGGGGGCTTTATTGAAAGTTTTGCTAGTGAAGAACTGGGGAGAATTCGTCGCAAGATCCAAGAG
AATGAAAGCAAGGTACGAGATCTTTTGCAAGAAATTCTCAAGAACAAGGGAGATATGCTAGCAGACCAGGTGGTGGCCAG
CCGGAATGGCCGCAATGTGCTGCCGGTTAAAAATACCTATCGGAATCGGATTCCAGGAGTGGTGCATGACATTTCTGCTA
GTGGAACGACCATTTATATCGAGCCAAGGGCAGTGGTCAATCTCAATGAGGAAATTTCCAACTACAAGGCGGACGAGCGC
TACGAACTCTTGCGAATTTTGCAAGAACTATCTGCTATGATTCGCCCTCATGCAGCTGAAATTGCCAACAATGCTTGGAT
CATCGGTCATCTTGACTTAGTGATGGCCAAGTTGGCCTTTATGCGAGAACGAGGAGCGGTAGTACCAGCCATATCCGATA
CACAAGCCATTCAGTTGCTACAGGTTCGTCATCCCCTGATTCAAAATGCAGTAGCTAATGACCTGCATTTCGGACCTGAT
TTAACAGAGATTGTTATTACTGGGCCAAATACCGGTGGTAAGACCATCATGTTGAAGACCTTGGGTCTGGCTCAGATCAT
GGCCCAATCAGGTCTGCCGATTTTGGCGGACAAGGGGAGTCGCGTTGGGATTTTCAGTCAGATTTTTGCAGACATTGGGG
ATGAGCAGTCCATTGAGCAGAGCCTGTCGACTTTCTCTAGTCACATGACCAATATCGTCTCTATTTTGGAGCAAGTTGAT
AGCGAGAGTCTGGTTCTGCTGGATGAGCTGGGAGCTGGGACTGACCCGCAGGAGGGTGCAGCTCTGGCTATTGCTATCTT
GGAAGATTTACGGTTAAGGCAGATTAAAACCATGGCGACGACCCACTATCCTGAGCTCAAAGCCTATGGGATTGAGACGG
ACTGGGTGGAAAATGCCAGCATGGAATTTGATACAGATAGTTTGCGACCGACTTATCGCTTTATGCAGGGAGTGCCTGGT
CGCTCCAATGCCTTTGAAATTGCTCGGCGTTTGGGCTTGTCTGAAGTTATCGTTAGCCATGCCCAAGAGCAGACCAACAC
AGACAGTGATGTCAATCAAATCATTGAGCGCTTGGAAGAGCAGACGCTGGAAAGTCGCAAGCGCTTGGATAATATTCGCG
AGGTGGAGCAGGAAAATCTCAAATTTAACCGAGCCCTCAAAAAACTTTACAATGAATTTAACCGAGAAAAAGAAACCGAA
CTCAATAAGGCACGCTTGGAAGCTCAGGAAATCGTTGATTTGGCTTTGTCAGAGAGTGAGAGCATTCTTAAAAATCTTCA
TGCTAAGTCCAGTCTCAAACCTCATGAGATTATTGAAGCCAAGGCTCAACTCAAAAAGTTGGCACCAGAAACAGTTGATT
TATCAAAGAATAAGGTACTCAAACAGGCCAAGAAAAATCGGGCGCCCAAGGTGGGAGATGATATCCTAGTCACCAGCTAT
GGTCAGCGGGGAACCTTGGTCAAGCTGCTCAAAGATGGCCGCTGGGAAGCTCAGGTAGGTCTCATCAAGATGACTCTAGA
GGAGCAGGAATTTAATCTCCTCAAGGCTGAAAAGGAACAGCAACCTAAGCGCAAGCAGGTCAATGTGGTCAAGCGAGCTA
ATACTGCTGGACCAAGAGCTAGACTGGATTTACGAGGTAAGCGTTATGAAGAAGCTATGAAAGAGCTAGATGAATTTATC
GATCAGGCCCTTCTTAATAATATGGCTCAGGTAGATATTATCCATGGTATCGGGACCGGGGTCATCCGTGAAGGAGTGAA
TAAATACCTCCGCCGCAACAAGCATGTCAAGTCCTTCGGCTATGCTCCGCAAAATGCTGGGGGCAGCGGTGCAACGATTG
TGATCTTTAAGTAA

Domains

Predicted by InterProScan.

MutS domain V (MutS_V)

(324-505)

Smr domain (Smr)

(702-777)

MutS2 and Smr-associated SH3 domain (MSSS)

(631-668)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A8AUW9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

39.163

100

0.398

Multiple sequence alignment