Detailed information NTG1000168

Bioinformatically predicted

Overview

• Name: recD/recD2/recDB
• Type: Machinery gene
• Locus tag: EL092_RS01290
• Genome accession: NZ_LR134291
• Coordinates: 271496..273862 (-)
• Length: 788 a.a.
• NCBI ID: WP_011999785.1
• Uniprot ID: A8AUW3
• Organism: Streptococcus gordonii strain NCTC7868
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 266496..278862

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL092_RS01260 (NCTC7868_00249)	-	267654..267980 (+)	327	WP_011999780.1	hypothetical protein	-
EL092_RS01270 (NCTC7868_00250)	-	268299..268682 (+)	384	Protein_249	CPBP family intramembrane glutamate endopeptidase	-
EL092_RS01275 (NCTC7868_00251)	-	268727..269476 (+)	750	WP_011999782.1	CPBP family intramembrane glutamic endopeptidase	-
EL092_RS01280 (NCTC7868_00252)	-	269552..270190 (+)	639	WP_011999783.1	TetR/AcrR family transcriptional regulator	-
EL092_RS01285 (NCTC7868_00253)	-	270495..271439 (-)	945	WP_011999784.1	hypothetical protein	-
EL092_RS01290 (NCTC7868_00254)	recD/recD2/recDB	271496..273862 (-)	2367	WP_011999785.1	ATP-dependent RecD-like DNA helicase	Machinery gene
EL092_RS01295 (NCTC7868_00255)	lepB	273957..274559 (-)	603	WP_011999786.1	signal peptidase I	-
EL092_RS01300 (NCTC7868_00256)	rnhC	274563..275453 (-)	891	WP_011999787.1	ribonuclease HIII	-
EL092_RS01305 (NCTC7868_00257)	-	275603..275908 (+)	306	WP_008808274.1	hypothetical protein	-
EL092_RS01310 (NCTC7868_00258)	-	275908..276456 (+)	549	WP_041789851.1	CvpA family protein	-
EL092_RS01315 (NCTC7868_00259)	mutS/mutS2	276512..278845 (+)	2334	WP_011999790.1	endonuclease MutS2	Machinery gene

Sequence

Protein

• Length: 788 a.a.
• Molecular weight: 88563.80 Da
• Isoelectric Point: 4.6406

>NTDB_id=1000168 EL092_RS01290 WP_011999785.1 271496..273862(-) (recD/recD2/recDB) [Streptococcus gordonii strain NCTC7868]
MEFYFSGTVERIIFENPNNFFRILLLDIEDTDAEFDDFEIIVTGTMADIMEGQDYTFWGTLVQHPKYGEQLKVTRYERAK
PTSKGLVKYFASDHFKGIGVKTAQKIIDLYGDNTIDQILADPSRLVSINGLSAVNREAFVSKLRQNYGTEMLLSKLAEYG
IPNKLALQIQDTYKEETLEIVQKYPYQLVEEIQGIGFKIADQLAQQLGIESDAPERFRAGLVHTLFSQSMETGDTYIEAR
DLLAHTIDLLENARQVELDPALVADELAHLIEEDKIQNVDTKIFENSLYFAEEGIRSNLIRILEKGKKETFGAPKLESII
EQVEQDLGICYDHIQKKAICDAINHKVFILTGGPGTGKTTVINGIIATYATLHKLDLAKKQELPILLAAPTGRAARRMNE
LTGLPSATIHRHLGMTGDDDTSHLDDYLDADFIIVDEFSMVDTWLANQLLSNISSNSKILIVGDADQLPSVSPGQVLADL
LKIRLLPQTKLTKIYRQGEDSTIVTLASQIQQGLLPANFTEKKADRSYFEASSEYIPDMIKKIVAAAIRSGIPAQDVQVL
APMYRGPAGIDQINQLMQDLINPSEKDQLVFEAPDCQYRQGDKVIHLVNDAESNVFNGDLGYITDLLPAKYTDSKQDELT
INFAGNEIVYQRSEWYKIRLAYAMSIHKSQGSEFPVVILPITKSSHRMLQRNLIYTAITRSKSKLVLLGEFSAFHYAVKN
TGTARKTYLVERFADLLEREEPAEVVTTNSDTDDPIPEDGFILTLDNYLSIDPMIGIREEDIKDIFKK

Nucleotide

• Length: 2367 bp

>NTDB_id=1000168 EL092_RS01290 WP_011999785.1 271496..273862(-) (recD/recD2/recDB) [Streptococcus gordonii strain NCTC7868]
ATGGAATTCTATTTTTCAGGAACCGTCGAACGCATTATATTTGAAAATCCCAACAATTTCTTTCGAATTTTGTTACTGGA
TATCGAGGACACAGATGCAGAATTTGATGATTTTGAGATCATTGTGACCGGAACCATGGCCGATATCATGGAAGGACAAG
ACTATACCTTTTGGGGAACTCTTGTCCAGCATCCCAAATACGGGGAACAGCTAAAAGTAACTCGCTACGAAAGAGCAAAG
CCAACTAGTAAGGGCCTGGTCAAGTATTTTGCTAGCGATCATTTTAAAGGGATCGGTGTTAAGACCGCCCAAAAGATAAT
AGACCTCTATGGAGATAATACGATTGACCAGATCTTAGCTGATCCTAGCCGGCTCGTAAGTATTAATGGCCTTTCTGCAG
TCAATCGGGAGGCCTTCGTCAGCAAACTTAGACAAAATTACGGCACAGAGATGTTGCTCTCTAAACTCGCTGAATATGGC
ATCCCCAATAAACTTGCCTTGCAGATTCAAGATACCTACAAAGAAGAAACGCTAGAAATTGTCCAAAAATATCCTTATCA
ACTAGTTGAAGAAATTCAAGGTATTGGTTTCAAAATAGCTGACCAGTTGGCCCAGCAACTTGGTATTGAAAGCGATGCTC
CAGAGCGTTTCCGAGCTGGTCTTGTTCATACCCTTTTCAGCCAATCTATGGAGACAGGTGATACTTATATAGAAGCACGT
GACTTGCTAGCCCACACCATTGATTTGCTGGAGAATGCCCGTCAGGTTGAACTTGATCCTGCCTTGGTAGCGGATGAGTT
GGCCCACCTCATTGAAGAAGATAAGATTCAAAACGTTGATACAAAAATCTTTGAAAACAGTCTTTATTTCGCCGAAGAAG
GTATCCGTAGCAATCTGATTCGGATTCTAGAAAAAGGCAAAAAAGAAACCTTTGGTGCCCCAAAACTCGAAAGTATCATC
GAACAAGTCGAGCAAGACTTAGGGATCTGCTATGACCATATTCAAAAGAAGGCCATCTGCGATGCCATTAATCATAAGGT
GTTTATTCTGACGGGTGGGCCAGGAACTGGTAAAACAACTGTTATCAACGGCATTATTGCTACTTATGCCACTCTTCACA
AGCTAGATTTAGCTAAAAAACAGGAATTACCTATTCTGCTTGCTGCTCCGACTGGACGCGCTGCCAGGCGAATGAATGAA
TTAACTGGACTCCCCAGTGCTACTATTCACCGGCATCTAGGGATGACTGGAGATGACGATACCAGCCATTTAGATGACTA
TTTGGATGCTGATTTCATCATTGTGGATGAGTTCTCTATGGTCGATACTTGGCTGGCCAATCAACTACTCAGCAATATTT
CTTCCAACAGCAAGATTCTCATTGTGGGGGATGCTGACCAACTTCCGTCTGTCAGTCCCGGTCAGGTTCTGGCTGATCTT
TTAAAAATACGTCTTTTACCCCAAACTAAACTGACAAAAATCTACCGGCAAGGAGAAGATTCAACAATTGTTACCCTGGC
CAGTCAAATCCAACAAGGACTTCTGCCGGCTAATTTTACTGAAAAAAAGGCGGATCGATCCTATTTCGAAGCGTCTAGCG
AGTATATCCCTGACATGATTAAGAAAATCGTAGCCGCCGCCATTCGCAGTGGCATCCCTGCCCAGGACGTCCAAGTCTTG
GCCCCTATGTATCGAGGACCCGCGGGAATCGACCAAATCAACCAACTTATGCAGGATTTGATAAATCCATCAGAAAAAGA
CCAACTGGTCTTTGAAGCACCAGACTGCCAGTACCGGCAAGGAGACAAGGTCATCCACCTGGTCAATGATGCTGAAAGCA
ATGTGTTTAATGGGGACTTGGGCTATATCACGGACTTGTTGCCAGCAAAATACACCGACTCTAAACAAGATGAACTAACC
ATCAACTTCGCTGGAAATGAAATCGTCTATCAACGTAGCGAATGGTACAAGATTCGCCTGGCCTATGCCATGAGTATTCA
TAAATCACAAGGTAGTGAATTTCCTGTCGTGATTCTGCCAATCACCAAGAGTAGCCACCGGATGTTGCAACGCAACCTCA
TCTATACAGCTATTACTCGCTCAAAAAGCAAGCTCGTTCTTTTAGGAGAATTTTCTGCCTTTCACTATGCTGTAAAAAAT
ACGGGCACAGCCCGCAAAACTTATCTGGTCGAGCGTTTTGCTGATCTTTTAGAAAGAGAAGAGCCTGCTGAAGTTGTCAC
CACTAATTCTGACACAGACGATCCAATTCCTGAAGATGGTTTTATCCTTACTCTTGATAACTACCTCAGTATTGATCCCA
TGATTGGAATTAGAGAAGAGGATATTAAAGATATTTTTAAAAAATAG

Domains

Predicted by InterProScan.

• Helix-hairpin-helix containing domain (HHH_RecD2) (146-236)

• AAA domain (AAA_30) (334-522)

• UvrD-like helicase C-terminal domain (UvrD_C_2) (661-708)

• ATP-dependent RecD-like DNA helicase SH3 domain (SH3_13) (573-643)

3D structure

• AlphaFold DB: A8AUW3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
recD/recD2/recDB	Bacillus subtilis subsp. subtilis str. 168	40.665	99.239	0.404