The Microbial Bioinformatics Group at the State Key Laboratory of Microbial Metabolism,
Shanghai Jiaotong University, is focused on genome mining
for bacterial mobile genetic elements, including:
(i) characterization of the genomic islands in Klebsiella pneumoniae and
the other opportunistic Gram-negative pathogens of the so-called "ESKAPE" group;
(ii) development of the bioinformatics tools/databases for island analysis;
(iii) identification of biosynthetic gene clusters for antibiotics in Streptomyces genomes.