SecReT4
Effector Protein ID: 82700711
T4SS name [ID]VirB [376]
Gene symbol-
Locus tagBAB1_1948
StrainBrucella melitensis biovar Abortus 2308
Repliconchromosome II [GenBank: NC_007618] [Browse all T4SS(s) in this replicon]
Location [Strand]1891813..1893099 [+]
Producthypothetical protein
Effector typeProtein
DescriptonBspF
T4CP requirementT4CP Indepedent
Target/EffectionBspA, BspB and BspF specifically inhibit host protein secretion and membrane trafficking along the secretory pathway.
UniProt IDQ2YLT8
KEGG IDbmf:BAB1_1948
PDB IDNA
Domain hit(s) vs Pfam Acetyltransf_6 [PF13480], Evalue: 7.7e-23, Aligned region: 224-366
Protein Sequence: 428 a.a.     [Download]
>gi|82700711|ref|YP_415285.1| hypothetical protein BAB1_1948 [Brucella melitensis biovar Abortus 2308]
MAAKPLLEESAGGNAAHLVSQLSDSSAVIEAAKKMEESLHSRDIPRKLAIYGAAAGFELRDELDHLSNRT
IEPNIFFNARFLAPAMPRLEDREVRFMVMRDENETRSRLRFVMPYTVERPGLPLSVPVIRSWATPFGPQG
TPLIDHDNPVGVVEDLFDILARRHIKLPEVLVLPEMRANGAAARLIRSVAIGRQLPVQSIEHKERPFLES
KLDGKTYIKEAIGAHHRHDYERLWRRLAEQGELVHKVARTPDEVRHAFEHFLTLEARGWKGRRGTAMAVD
RFRAAFAREAVNNLAECDCVRIHTLELDGRVIAILIVFTVSGEAWTWKTAYDETFHAWSPGVLLMIEVVK
NHLDDPNIARTDSCAVPDHPVMTRLFRERETMETLVVGLHPGADRLVRQAASQIHLYQRTRNLARIIRNR
LRSFTEHK
-
Nucleotide Sequence: 1287 bp     [Download]
>gi|82698932|ref|NC_007618.1|:1891813-1893099 Brucella melitensis biovar Abortus 2308 chromosome I, complete sequence
ATGGCTGCAAAACCTTTGCTTGAGGAATCAGCAGGCGGAAACGCCGCCCATCTTGTTTCGCAACTTTCCG
ACAGCAGCGCCGTGATCGAAGCGGCGAAGAAGATGGAGGAAAGCCTGCACAGCCGCGATATTCCGCGCAA
GCTTGCCATTTATGGCGCAGCAGCCGGTTTTGAATTGCGTGATGAGCTGGACCATCTGAGCAATCGCACC
ATAGAGCCGAACATCTTCTTCAACGCACGTTTTCTGGCGCCTGCCATGCCACGCCTTGAAGACCGTGAAG
TTCGCTTCATGGTCATGCGCGACGAAAATGAAACCCGAAGCCGTCTGCGCTTTGTGATGCCCTATACGGT
GGAACGCCCCGGCCTGCCACTTTCGGTTCCCGTGATTCGCTCCTGGGCCACCCCCTTCGGCCCGCAGGGC
ACGCCGCTCATCGACCATGACAACCCGGTCGGGGTGGTTGAAGACCTGTTCGACATTCTGGCGCGCAGGC
ACATCAAGCTGCCCGAAGTACTGGTTTTGCCGGAAATGCGTGCCAATGGAGCAGCCGCCAGGCTGATCCG
CTCGGTCGCCATCGGGCGCCAATTGCCGGTTCAATCCATCGAGCACAAGGAACGTCCCTTCCTTGAAAGC
AAGCTCGATGGCAAGACCTATATAAAGGAAGCCATCGGGGCGCATCATCGCCATGACTATGAACGATTGT
GGCGCCGCCTTGCCGAGCAGGGCGAACTCGTTCACAAGGTTGCCCGCACGCCCGATGAGGTGCGCCATGC
CTTTGAACATTTCCTCACACTGGAGGCGCGCGGCTGGAAGGGACGTCGCGGCACAGCCATGGCTGTTGAC
CGTTTTCGTGCCGCTTTCGCGCGCGAAGCCGTCAACAATCTTGCCGAATGCGACTGTGTACGCATTCACA
CGCTGGAACTTGATGGCAGGGTCATCGCAATCCTCATCGTCTTCACGGTATCAGGCGAAGCCTGGACCTG
GAAAACCGCCTATGACGAGACATTTCATGCCTGGTCGCCCGGCGTTCTCCTGATGATCGAAGTGGTGAAG
AACCACCTGGACGACCCCAATATCGCCCGCACCGATTCCTGCGCCGTGCCAGACCATCCCGTCATGACGC
GCCTCTTCCGTGAACGCGAGACTATGGAAACGCTTGTCGTCGGCCTTCACCCCGGCGCGGATCGGCTGGT
GCGGCAGGCGGCATCGCAGATTCACCTCTATCAGCGCACCCGCAATCTCGCGCGCATCATCCGCAACCGG
CTGCGCAGTTTCACCGAGCATAAATAA

Reference
(1) Myeni S et al. (2013). Brucella modulates secretory trafficking via multiple type IV secretion effector proteins. PLoS Pathog. 9(8):e1003556. [PudMed:23950720] experimental in_silico
 
experimental experimental literature
in_silico in silico analysis literature